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Plasma based surface modication of poly (dimethylsiloxane) electrospun membrane proper for organ-on-a-chip applications

Kiyoumarsioskouei, A ; Sharif University of Technology | 2019

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  1. Type of Document: Article
  2. DOI: 10.24200/sci.2018.20148
  3. Publisher: Sharif University of Technology , 2019
  4. Abstract:
  5. onstructing of the scaffolds for cell culture applications has long been of interest for engineering researchers and biologist. In this study, a novel process is utilized for construction of suitable membrane with a high mechanical strength and appropriate surface behavior. Poly (dimethylsiloxane) (PDMS) is electrospun into fine fibers using poly (methyl methacrylate) (PMMA) as the carrier polymer in different weight ratios. Since the surface behavior of all PDMS substrates is moderately hydrophobic (120 < contact angle (CA) < 150), the electrospun membranes with higher PDMS ratios show slightly higher hydrophilicity. Direct plasma treatment is utilized to change the interfacial wettability of the membrane. Applying plasma changes the surface energy and renders the PDMS/PMMA substrates superhydrophilic (CA
  6. Keywords:
  7. Biomechanics ; Cell culture ; Cell engineering ; Contact angle ; Esters ; Hydrophilicity ; Hydrophobicity ; Microchannels ; Plasma applications ; Tensile testing ; Yield stress ; Electrospun membranes ; Flexible membranes ; High mechanical strength ; Poly(methyl methacrylate) (PMMA) ; Polydimethylsiloxane PDMS ; Super-hydrophilic ; Super-hydrophobic surfaces ; Superhydrophilic surface ; Membranes ; Bioenergetics ; Electronic equipment ; Genetic engineering ; Membrane ; Plasma ; Tensile stress ; Wettability
  8. Source: Scientia Iranica ; Volume 26, Issue 2 , 2019 , Pages 808-814 ; 10263098 (ISSN)
  9. URL: http://scientiairanica.sharif.edu/article_20148.html