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The enhanced human vs. the virtuous human: a post-phenomenological perspective
, Article AI and Society ; Volume 36, Issue 3 , 2021 , Pages 1057-1068 ; 09515666 (ISSN) ; Taqavi, M ; Sharif University of Technology
Springer Science and Business Media Deutschland GmbH
2021
Abstract
The new generations of bioenhancement technologies and traditional Virtue Theory both try to make a meaningful connection between the improvement of human states and characteristics on one hand, and attainment to the good life, on the other. Considering the main elements of virtuousness in Farabi’s thought—namely rational inquiry and deliberative insights, alongside volitional discipline within various social contexts, one can conclude that although the trajectories of enhancement technologies—be they in the field of genetic engineering, neurostimulation technologies, or pharmacology—do not in themselves satisfy the constitutive determinants of virtuousness, they function as having both...
The enhanced human vs. the virtuous human: a post-phenomenological perspective
, Article AI and Society ; 2020 ; Taqavi, M ; Sharif University of Technology
Springer Science and Business Media Deutschland GmbH
2020
Abstract
The new generations of bioenhancement technologies and traditional Virtue Theory both try to make a meaningful connection between the improvement of human states and characteristics on one hand, and attainment to the good life, on the other. Considering the main elements of virtuousness in Farabi’s thought—namely rational inquiry and deliberative insights, alongside volitional discipline within various social contexts, one can conclude that although the trajectories of enhancement technologies—be they in the field of genetic engineering, neurostimulation technologies, or pharmacology—do not in themselves satisfy the constitutive determinants of virtuousness, they function as having both...
Intrusion detection using a fuzzy genetics-based learning algorithm
, Article Journal of Network and Computer Applications ; Volume 30, Issue 1 , 2007 , Pages 414-428 ; 10848045 (ISSN) ; Habibi, J ; Lucas, C ; Sharif University of Technology
2007
Abstract
Fuzzy systems have demonstrated their ability to solve different kinds of problems in various applications domains. Currently, there is an increasing interest to augment fuzzy systems with learning and adaptation capabilities. Two of the most successful approaches to hybridize fuzzy systems with learning and adaptation methods have been made in the realm of soft computing. Neural fuzzy systems and genetic fuzzy systems hybridize the approximate reasoning method of fuzzy systems with the learning capabilities of neural networks and evolutionary algorithms. The objective of this paper is to describe a fuzzy genetics-based learning algorithm and discuss its usage to detect intrusion in a...
Genome Engineering of Bacillus Subtilis Using CRISPR Technology to Overproduce Protease Production
, M.Sc. Thesis Sharif University of Technology ; Roostaazad, Reza (Supervisor) ; Banaei Moghaddam, Ali Mohammad (Supervisor)
Abstract
Enzymes are an important part of detergents, they reduce the activation energy of the reaction and thus increase the efficiency of the process. Protease enzyme is one of the most common enzymes in detergents. Bacillus strain is the most important strain in the production of this enzyme and among the species of Bacillus, Bacillus subtilis is the most used. Bacillus subtilis is a gram-positive, rod-shaped bacterium. This bacterium is considered a non-pathogenic cell that has the ability to form spores and prevent death and damage in harsh conditions. In this study, CRISPR system was used to modify the genome of Bacillus subtilis ATCC 6633 in order to increase alkaline protease. To increase the...
All-optical DNA variant discovery utilizing extended DV-curve-based wavelength modulation
, Article Journal of the Optical Society of America A: Optics and Image Science, and Vision ; Volume 35, Issue 11 , 2018 , Pages 1929-1940 ; 10847529 (ISSN) ; Babashah, H ; Koohi, S ; Kavehvash, Z ; Sharif University of Technology
OSA - The Optical Society
2018
Abstract
This paper presents a novel optical processing approach for exploring genome sequences built upon an optical correlator for global alignment and the extended dual-vector-curve-curve (DV-curve) method for local alignment. To overcome the problem of the traditional DV-curve method for presenting an accurate and simplified output, we propose the hybrid amplitude wavelength polarization optical DV-curve (HAWPOD) method, built upon the DV-curve method, to analyze genome sequences in three steps: DNA coding, alignment, and post-Analysis. For this purpose, a tunable graphene-based color filter is designed for wavelength modulation of optical signals. Moreover, all-optical implementation of the...
A hybrid method of pareto, TOPSIS and genetic algorithm to optimize multi-product multi-constraint inventory control systems with random fuzzy replenishments
, Article Mathematical and Computer Modelling ; Volume 49, Issue 5-6 , 2009 , Pages 1044-1057 ; 08957177 (ISSN) ; AkhavanNiaki, T ; Aryanezhad, M. B ; Sharif University of Technology
2009
Abstract
Multi-periodic inventory control problems are mainly studied employing one of two assumptions. The first is the continuous review, where depending on the inventory level, orders can be placed at any time, and the other is the periodic review, where orders can be placed only at the beginning of each period. In this paper, we relax these assumptions and assume that the time-periods between two replenishments are random fuzzy variables. While in the model of the problem at hand the decision variables are of integer type and there are space and service level constraints, for the shortages we consider a combination of back-order and lost-sales. We show the model of this problem to be an...
Increase Production of the Enzyme by Cell Genetic Modification
, M.Sc. Thesis Sharif University of Technology ; Roosta Azad, Reza (Supervisor) ; Banaei Moghaddam, Ali Mohammad (Supervisor)
Abstract
Genetic engineering of cells has been one of the most effective ways to increase protein production in wild strains. Among the various genetic engineering techniques, the CRISPR/Cas9 system that directly edits the cell chromosome, yielding greater efficiency and easier operation. In this study, we used this system to modify the genome of Bacillus subtilis ATCC 6633 to increase the production of extracellular alkaline protease enzyme. Alkaline protease enzyme has many applications in different industries, but in this study, the application of this enzyme in the detergent industry has been considered. To increase the production of this enzyme, we disrupted and prevented the gene responsible...
Economic and economic-statistical designs of MEWMA control charts - A hybrid Taguchi loss, Markov chain, and genetic algorithm approach
, Article International Journal of Advanced Manufacturing Technology ; Volume 48, Issue 1-4 , 2010 , Pages 283-296 ; 02683768 (ISSN) ; Ershadi, M. J ; Malaki, M ; Sharif University of Technology
Abstract
Economic design of multivariate exponentially weighted moving average (MEWMA) control charts for monitoring the process mean vector involves determining economically the optimum values of the three control parameters: the sample size, the sampling interval between successive samples, and the control limits or the critical region of the chart. In the economic-statistical design, constraints (including the requirements of type I error probability and power) are added such that the statistical property of the chart is satisfied. In this paper, using the multivariate Taguchi loss approach, the Lorenzen-Vance (Technometrics 28:3-10, 1) cost function of implementing the control chart is extended...
Optimizing the multi-product, multi-constraint, bi-objective newsboy problem with discount by a hybrid method of goal programming and genetic algorithm
, Article Engineering Optimization ; Volume 41, Issue 5 , 2009 , Pages 437-457 ; 0305215X (ISSN) ; Akhavan Niaki, T ; Hoseini, V ; Sharif University of Technology
2009
Abstract
This article points out the real-world prevalence of the multiple-product, multiple-constraint newsboy problem with two objectivesthe 'newsstand problem'in which there are total and incremental discounts on purchasing prices. The constraints are the warehouse capacity and the batch forms of the order placements. The first objective of this problem is to find the order quantities that maximize expected profit, and the second objective is maximizing the service rate. It is assumed that the holding and shortage costs, modelled by a quadratic function, occur at the end of the period. Moreover, the decision variables are integer. A formulation of the problem is presented and shown to be an...
Plasma based surface modication of poly (dimethylsiloxane) electrospun membrane proper for organ-on-a-chip applications
, Article Scientia Iranica ; Volume 26, Issue 2 , 2019 , Pages 808-814 ; 10263098 (ISSN) ; Saidi, M. S ; Moghadas, H ; Firoozabadi, B ; Sharif University of Technology
Sharif University of Technology
2019
Abstract
Electrospun porous membrane; Superhydrophilic surfaces; Superhydrophobic surfaces; Cell culture; Organ on a chip; Flexible membrane; Strong membrane; Surface modications
Plasma based surface modication of poly (dimethylsiloxane) electrospun membrane proper for organ-on-a-chip applications
, Article Scientia Iranica ; Volume 26, Issue 2 , 2019 , Pages 808-814 ; 10263098 (ISSN) ; Saidi, M. S ; Moghadas, H ; Firoozabadi, B ; Sharif University of Technology
Sharif University of Technology
2019
Abstract
onstructing of the scaffolds for cell culture applications has long been of interest for engineering researchers and biologist. In this study, a novel process is utilized for construction of suitable membrane with a high mechanical strength and appropriate surface behavior. Poly (dimethylsiloxane) (PDMS) is electrospun into fine fibers using poly (methyl methacrylate) (PMMA) as the carrier polymer in different weight ratios. Since the surface behavior of all PDMS substrates is moderately hydrophobic (120 < contact angle (CA) < 150), the electrospun membranes with higher PDMS ratios show slightly higher hydrophilicity. Direct plasma treatment is utilized to change the interfacial wettability...
A high-performance vector-controlled PMSM drive with maximum torque per ampere operation
, Article 2008 IEEE 2nd International Power and Energy Conference, PECon 2008, Johor Baharu, 1 December 2008 through 3 December 2008 ; January , 2008 , Pages 254-258 ; 9781424424054 (ISBN) ; Nademi, H ; Rezaei, M ; Sharif University of Technology
2008
Abstract
Permanent magnet synchronous motor (PMSM) drives have many advantages over other drives, e.g. high efficiency and high power density. Particularly, permanent magnet synchronous motors are epoch-making and are intensively studied among researchers, scientists and engineers. This paper deals with a novel high performance controller based on genetic algorithm. The scheme allows the motor to be driven with maximum torque per ampere characteristic. In this paper assuming an appropriate fitness function, the optimum values for d-axis current of motor set points at each time are found and then applied to the controller. Simulation results show the successful operation of the proposed controller. ©...
On the power of power analysis in the real world: A complete break of the KeeLoq code hopping scheme
, Article 28th Annual International Cryptology Conference, CRYPTO 2008, Santa Barbara, CA, 17 August 2008 through 21 August 2008 ; Volume 5157 LNCS , 2008 , Pages 203-220 ; 03029743 (ISSN) ; 3540851739 (ISBN); 9783540851738 (ISBN) ; Kasper, T ; Moradi, A ; Paar, C ; Salmasizadeh, M ; Manzuri Shalmani, M. T ; Sharif University of Technology
2008
Abstract
KeeLoq remote keyless entry systems are widely used for access control purposes such as garage openers or car door systems. We present the first successful differential power analysis attacks on numerous commercially available products employing KeeLoq code hopping. Our new techniques combine side-channel cryptanalysis with specific properties of the KeeLoq algorithm. They allow for efficiently revealing both the secret key of a remote transmitter and the manufacturer key stored in a receiver. As a result, a remote control can be cloned from only ten power traces, allowing for a practical key recovery in few minutes. After extracting the manufacturer key once, with similar techniques, we...
Trajectory tracking of a mobile robot using fuzzy logic tuned by genetic algorithm
, Article International Journal of Engineering, Transactions A: Basics ; Volume 19, Issue 1 , 2006 , Pages 95-104 ; 17281431 (ISSN) ; Mahboobi, S. H ; Alasty, A ; Sharif University of Technology
Materials and Energy Research Center
2006
Abstract
In recent years, soft computing methods, like fuzzy logic and neural networks have been presented and developed for the purpose of mobile robot trajectory tracking. In this paper we will present a fuzzy approach to the problem of mobile robot path tracking for the CEDRA rescue robot with a complicated kinematical model. After designing the fuzzy tracking controller, the membership functions and rule weights will be optimized by genetic algorithm in order to obtain more acceptable results. Simulation results have demonstrated significant improvements in controller efficacy
Enhancement of the tipover stability of mobile manipulators with non-holonomic constraints using an adaptive neuro-fuzzy-based controller
, Article Proceedings of the Institution of Mechanical Engineers. Part I: Journal of Systems and Control Engineering ; Volume 223, Issue 2 , 2009 , Pages 201-213 ; 09596518 (ISSN) ; Meghdari, A ; Naderi, D ; Eslami, S ; Sharif University of Technology
2009
Abstract
The stability issue of mobile manipulators, particularly when the end-effector and the vehicle have to follow a predefined trajectory (for some special duties like painting a plane or carrying a light load), is a crucial subject and needs special attention. In this paper, by utilizing the manipulator compensation motions, the instantaneous proper configuration for a redundant mobile robot is determined. A fast methodology taking into account the dynamic interaction between the manipulator and the vehicle is proposed for enhancing the tipover stability (i.e. stability against overturning) of the mobile manipulator by employing the soft computing approach including a genetic algorithm, neural...