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Plasma based surface modication of poly (dimethylsiloxane) electrospun membrane proper for organ-on-a-chip applications
, Article Scientia Iranica ; Volume 26, Issue 2 , 2019 , Pages 808-814 ; 10263098 (ISSN) ; Saidi, M. S ; Moghadas, H ; Firoozabadi, B ; Sharif University of Technology
Sharif University of Technology
2019
Abstract
Electrospun porous membrane; Superhydrophilic surfaces; Superhydrophobic surfaces; Cell culture; Organ on a chip; Flexible membrane; Strong membrane; Surface modications
Plasma based surface modication of poly (dimethylsiloxane) electrospun membrane proper for organ-on-a-chip applications
, Article Scientia Iranica ; Volume 26, Issue 2 , 2019 , Pages 808-814 ; 10263098 (ISSN) ; Saidi, M. S ; Moghadas, H ; Firoozabadi, B ; Sharif University of Technology
Sharif University of Technology
2019
Abstract
onstructing of the scaffolds for cell culture applications has long been of interest for engineering researchers and biologist. In this study, a novel process is utilized for construction of suitable membrane with a high mechanical strength and appropriate surface behavior. Poly (dimethylsiloxane) (PDMS) is electrospun into fine fibers using poly (methyl methacrylate) (PMMA) as the carrier polymer in different weight ratios. Since the surface behavior of all PDMS substrates is moderately hydrophobic (120 < contact angle (CA) < 150), the electrospun membranes with higher PDMS ratios show slightly higher hydrophilicity. Direct plasma treatment is utilized to change the interfacial wettability...