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KF/Al2O3-mediated N-alkylation of amines and nitrogen heterocycles and S-alkylation of thiols

Matloubi Moghaddam , F ; Sharif University of Technology | 2006

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  1. Type of Document: Article
  2. DOI: 10.1080/00397910600943634
  3. Publisher: 2006
  4. Abstract:
  5. KF/Al2O3 efficiently catalyzes N-alkylation of heterocyclic, primary, and secondary amines and S-alkylation of thiols with a variety of alkyl halides. The N-alkylation and S-alkylation adducts were produced in good to excellent yields and in short times. Copyright © Taylor & Francis Group, LLC
  6. Keywords:
  7. Aluminum oxide ; Amine ; Halide ; Nitrogen ; Thiol ; Alkylation ; Catalysis ; Drug synthesis
  8. Source: Synthetic Communications ; Volume 36, Issue 23 , 2006 , Pages 3599-3607 ; 00397911 (ISSN)
  9. URL: https://www.tandfonline.com/doi/abs/10.1080/00397910600943634?journalCode=lsyc20