Sharif Digital Repository

The current study investigates the conjugate heat transfer characteristics for laminar flow in backward facing step channel. All of the channel walls are insulated except the lower thick wall under a constant temperature. The upper wall includes a insulated obstacle perpendicular to flow direction. The effect of obstacle height and location on the fluid flow and heat transfer are numerically explored for the Reynolds number in the range of 10 ≤ Re ≤ 300. Incompressible Navier-Stokes and thermal energy equations are solved simultaneously in fluid region by the upwind compact finite difference scheme based on flux-difference splitting in conjunction with artificial compressibility method. In... 

In the present study criterion for local thermal equilibrium assumption is studied. It concerns with the fluid flow and heat transfer between two parallel plates filled with a saturated porous medium under non-equilibrium condition. A two-equation model is utilized to represent the fluid and solid energy transport. Numerical Finite Volume Method has been developed for solving coupled energy equations and the Non-Darcian effects are considered for description of momentum equation. The effects of suitable non dimensional parameters as Peclet number and conductivity ratio has been studied thoroughly. A suitable non dimensional equation proposed in wide range of Peclet number and conductivity... 

Bioreactor system has been used in bone tissue engineering in order to simulate dynamic nature of bone tissue environments. Perfusion bioreactors have been reported as the most efficient types of shear-loading bioreactor. Also, combination of forces, such as rotation plus perfusion, has been reported to enhance cell growth and osteogenic differentiation. Mathematical modeling using sophisticated infrastructure processes could be helpful and streamline the development of functional grafts by estimating and defining an effective range of bioreactor settings for better augmentation of tissue engineering. This study is aimed to conduct computational modeling for newly designed bioreactors in... 

In this research, the centrifugal compressor of a turbocharger is investigated experimentally and numerically. Performance characteristics of the compressor were obtained experimentally by measurements of rotor speed and flow parameters at the inlet and outlet of the compressor. Three dimensional flow field in the impeller and diffuser was analyzed numerically using a full Navier-Stokes program with SST turbulence model. The performance characteristics of the compressor were obtained numerically, which were then compared with the experimental results. The comparison shows good agreement. Furthermore, the effect of area ratio and tip clearance on the performance parameters and flow field was... 

Production from gas condensate reservoirs requires precise determination of reservoir fluid properties along with their positive impact on real reservoir performance evaluation and fluid in place volume calculation. This fact is particularly important because liquid drop out phenomena occurs as a result of pressure drop due to fluid production and condensate remains in reservoir [Mohebzadeh, 2005. In this study the challenges and problems of fluid phase behavior simulation in southern Iranian retrograde gas condensate reservoirs is discussed. Most of the problems and challenges are inaccuracy of equation of states near the critical point, special conditions and produced fluid flow... 

Circulating tumor cells (CTCs) isolation from a blood sample plays an important role in cancer diagnosis and treatment. Microfluidics offers a great potential for cancer cell separation from the blood. Among the microfluidic-based methods for CTC separation, the inertial method as a passive method and magnetic method as an active method are two efficient well-established methods. Here, we investigated the combination of these two methods to separate CTCs from a blood sample in a single chip. Firstly, numerical simulations were performed to analyze the fluid flow within the proposed channel, and the particle trajectories within the inertial cell separation unit were investigated to... 

The separation of cancer cells from a heterogeneous biological sample such as blood plays a vital role in cancer study and future treatments. In this paper, we designed and investigated two microfluidic devices for cancer cell separation, including a serpentine inertial device and an integrated inertial-magnetophoretic device. Firstly, numerical modeling was carried out to study the fluid flow, particles’ trajectories in the inertial device. Then the device was fabricated using soft photolithography and suspension of two types of microparticles with the size of 10 and 15 µm were injected into the microchannel separately to investigate the particles’ trajectories and focusing behavior at... 

The separation of cancer cells from a heterogeneous biological sample such as blood plays a vital role in cancer study and future treatments. In this paper, we designed and investigated two microfluidic devices for cancer cell separation, including a serpentine inertial device and an integrated inertial-magnetophoretic device. Firstly, numerical modeling was carried out to study the fluid flow, particles’ trajectories in the inertial device. Then the device was fabricated using soft photolithography and suspension of two types of microparticles with the size of 10 and 15 µm were injected into the microchannel separately to investigate the particles’ trajectories and focusing behavior at... 

The aim of this research is to design an implantable integrated microfluidic system in order to regularly measure the glucose level in the human body, nonenzymatically, using the microdialysis method. The main compartments of this system are a micropump, array of hollow microneedles and an electrochemical sensor. At the base of the microneedles, there are located semipermeable membranes, that when the pumped dialysis fluid passes over them, the glucose of the interstitial fluid diffuses into the dialysis fluid and then, in the sensor section, it is measured nonenzymatically using the amperometry method. Both the arrangement of the miconeedles and the amount of the dialysis fluid flow are... 

The density jump on an inclined surface is analyzed using an integral method by applying mass and momentum conservation equations. The jump occurs in a two-layered fluid flow in which the upper layer is stagnant and very deep. A relation is derived, which gives the conjugate depth ratio as a function of inlet densimetric Froude number, inlet concentration ratio, bed slope and entrainment. A set of experiments are performed to verify the relation. The theory and the measurements are in good agreement. The analysis reveals that increasing the surface inclination results in a decrease in the conjugate depth ratio. This analysis also shows that the densimetric Froude number just after the jump... 

Adomian decomposition method was employed to obtain an approximate solution to two-dimensional and axisymmetric jet impinging flows in this work. Assumptions have been made to reduce the related full Navier-Stokes equations to a non-linear ordinary differential equation. A trial and error strategy has been used to obtain the constant coefficient in the approximated solution. Velocity Profiles, Shear stresses and displacement thickness were chosen to be compared with accurate numerical data. Sensitivity of the results to the number of terms have been discussed. The results showed for open boundary problems having at least one boundary condition at infinity, the applicable range of the... 

COMSOL Multiphysics is a comprehensive simulation software environment for a wide range of applications. COMSOL has an interactive interface that facilitates the modeling procedure and allows an easy coupling of different physical processes. The Subsurface Flow module extends the COMSOL modeling environment to applications related to fluid flow in saturated and variably saturated porous media. COMSOL is increasingly used in the investigation of geophysical, hydrogeological and environmental phenomena. The main goal of this work is to explore the ability of COMSOL for simulating seawater intrusion (SWI) in fractured coastal aquifers. Numerical modeling of such a problem is of high interest as... 

A sequential implicit numerical method based on discrete-fracture model and the Galerkin Finite Element method, for time-dependent coupled fluid flow and geomechanics problems in fractured subsurface formations is presented. Discrete-fracture model has been used to explicitly represent the fracture network inside porous media. The Galerkin Finite Element method with adaptive unstructured gridding is implemented to numerically solve the spatially three-dimensional and time-dependent problem. The presented method is validated with previously obtained solutions. Two problems are numerically solved by applying the presented methodology in a three-dimensional fractured petroleum reservoir under... 

A numerical model has been developed for studying the flow and heat transfer characteristics of single phase liquid flow through a microchannel. In this work the heat transfer characteristics of pressure driven and electroosmotic flow through microchannels have been studied. The governing equations are the Poisson-Boltzmann and Navier-Stokes equations which have been solved numerically using the standard Galerkin and the Mixed 4-1 finite element methods, respectively. Finally the energy equation is solved numerically using the Stream-wise Upwind Petrov Galerkin (SUPG) method. Two dimensional Poisson-Boltzmann equation was first solved to find the electric potential field and net charge... 

Net fluid flow of soap films induced by (ac or dc) electric fields in asymmetric frames is presented. Previous experiments of controllable soap film flow required the simultaneous use of an electrical current passing through the film and an external electric field or the use of nonuniform ac electric fields. Here a single voltage difference generates both the electrical current going through the film and the electric field that actuates on the charge induced on the film. The film is set into global motion due to the broken symmetry that appears by the use of asymmetric frames. If symmetric frames are used, the film flow is not steady but time dependent and irregular. Finally, we study... 

Successful designs for an injection process to improve reservoir recovery seek more accurate values of saturation dependent functions, including relative permeability curves. The ignorance on underlying heterogeneity (e.g. layering) might lead to inaccurate predicting of flow behavior in layered heterogeneous porous media. Analysis of experimental core flood results in composite core systems (the system) along with numerical simulation at the core scale can provide an insight into this problem, especially when the capillary effects are present. In this study unsteady state two phase displacements have been conducted on the system with different internal arrangements. The main contribution is... 

Acidizing is one of the most effective techniques to remove the formation damage and restore (or even increase) the permeability of the near wellbore region. Although this technique is widely used to resolve the skin problem, it could initiate new damages itself that hinder the fluid flow and decrease the well production, consequently. Acid-oil emulsion and sludge formation are known as two major induced formation damage and the main reasons for the oil well acid treatment failures. Despite its critical effects, no comprehensive study has been addressed this specific type of formation damages in details. In this study, the acid-oil emulsion and asphaltic sludge formation were evaluated... 

SUMMARY: In this paper, a numerical model is developed for the fully coupled hydro-mechanical analysis of deformable, progressively fracturing porous media interacting with the flow of two immiscible, compressible wetting and non-wetting pore fluids, in which the coupling between various processes is taken into account. The governing equations involving the coupled solid skeleton deformation and two-phase fluid flow in partially saturated porous media including cohesive cracks are derived within the framework of the generalized Biot theory. The fluid flow within the crack is simulated using the Darcy law in which the permeability variation with porosity because of the cracking of the solid... 

In this paper, a fully coupled numerical model is developed for the modeling of the hydraulic fracture propagation in porous media using the extended finite element method in conjunction with the cohesive crack model. The governing equations, which account for the coupling between various physical phenomena, are derived within the framework of the generalized Biot theory. The fluid flow within the fracture is modeled using the Darcy law, in which the fracture permeability is assumed according to the well-known cubic law. By taking the advantage of the cohesive crack model, the nonlinear fracture processes developing along the fracture process zone are simulated. The spatial discretization... 

Most of the heavy oil reservoirs contain discontinuous shale which affects fluid flow through porous media as well as recovery efficiency during enhanced oil recovery processes. However, the role of shale geometrical characteristics (including orientation, length, discontinuity, and spacing of the shale) on oil recovery remains a topic of debate in the literature, especially during miscible injection of heavy oils and five-spot systems. Here, a series of hydrocarbon solvent injection tests have been performed on various five-spot glass micromodels containing barriers which are initially saturated with heavy oil under fixed flow rate conditions. Oil recoveries as a function of pore volumes of...