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Various reduced-order surrogate models for fluid flow and mass transfer in human bronchial tree
, Article Biomechanics and Modeling in Mechanobiology ; Volume 20, Issue 6 , 2021 , Pages 2203-2226 ; 16177959 (ISSN) ; Bozorgmehry Boozarjomehry, R ; Sharif University of Technology
Springer Science and Business Media Deutschland GmbH
2021
Abstract
The bronchial tree plays a main role in the human respiratory system because the air distribution throughout the lungs and gas exchange with blood occur in the airways whose dimensions vary from several centimeters to micrometers. Organization of about 60,000 conducting airways and 33 million respiratory airways in a limited space results in a complex structure. Due to this inherent complexity and a high number of airways, using target-oriented dimensional reduction is inevitable. In addition, there is no general reduced-order model for various types of problems. This necessitates coming up with an appropriate model from a variety of different reduced-order models to solve the desired...
Various reduced-order surrogate models for fluid flow and mass transfer in human bronchial tree
, Article Biomechanics and Modeling in Mechanobiology ; Volume 20, Issue 6 , 2021 , Pages 2203-2226 ; 16177959 (ISSN) ; Bozorgmehry Boozarjomehry, R ; Sharif University of Technology
Springer Science and Business Media Deutschland GmbH
2021
Abstract
The bronchial tree plays a main role in the human respiratory system because the air distribution throughout the lungs and gas exchange with blood occur in the airways whose dimensions vary from several centimeters to micrometers. Organization of about 60,000 conducting airways and 33 million respiratory airways in a limited space results in a complex structure. Due to this inherent complexity and a high number of airways, using target-oriented dimensional reduction is inevitable. In addition, there is no general reduced-order model for various types of problems. This necessitates coming up with an appropriate model from a variety of different reduced-order models to solve the desired...
Analytical study of fluid flow modeling by diffusivity equation including the quadratic pressure gradient term
, Article Computers and Geotechnics ; Volume 89 , 2017 , Pages 1-8 ; 0266352X (ISSN) ; Izadmehr, M ; Karimi, M ; Sharifi, M ; Kazemi, A ; Sharif University of Technology
Abstract
Diffusivity equation which can provide us with the pressure distribution, is a Partial Differential Equation (PDE) describing fluid flow in porous media. The quadratic pressure gradient term in the diffusivity equation is nearly neglected in hydrology and petroleum engineering problems such as well test analysis. When a compressible liquid is injected into a well at high pressure gradient or when the reservoir possess a small permeability value, the effect of ignoring this term increases. In such cases, neglecting this parameter can result in high errors. Previous models basically focused on numerical and semi-analytical methods for semi-infinite domain. To the best of our knowledge, no...