Sharif Digital Repository

Microfluidic devices have been widely used for biological and cellular studies. Microbioreactors for three-dimensional (3D) multicellular spheroid culture are now considered as the next generation in in vitro diagnostic tools. The feasibility of using 3D cell aggregates to form multicellular spheroids in a microbioreactor with U-shaped barriers has been demonstrated experimentally. A barrier array is an alternative to commonly used microwell traps. The present study investigates oxygen and glucose concentration distributions as key parameters in a U-shaped array microbioreactor using finite element simulation. The effect of spheroid diameter, inlet concentration and flow rate of the medium... 

Optical and thermal analysis of the most well-known solar concentrator system; parabolic trough collector (PTC) are investigated and analyzed. To evaluate performance of the PTC, four cities of Iran with different weather conditions are chosen as case studies. Effective parameters such as concentration ratio, incident angle correction factor, collector mass flow rate are considered. The main objective of this work is evaluation of the solar energy potential using PTC in under consideration cities with different climates. Numerical modeling of the analysis is done using MATLAB software. Simulation results shows that Shiraz, with an average annual thermal efficiency of 13.91% and annual useful... 

In this paper, an extended finite element method is presented for simulation of interaction between hydraulic fracturing and natural fractures in saturated porous media. The well-known u−p formulation is employed in order to obtain the fully coupled set of governing equations. Natural faults are modeled for both opening and closure modes where the fluid inflow and contact conditions are considered at the interface, respectively. The Darcy law is employed in conjunction with an aperture dependent permeability for the fracture channel to describe the interfacial inflow. The contact constraints of both the solid and fluid phases are imposed using the Penalty method. The Heaviside and modified... 

Successful designs for an injection process to improve reservoir recovery seek more accurate values of saturation dependent functions, including relative permeability curves. The ignorance on underlying heterogeneity (e.g. layering) might lead to inaccurate predicting of flow behavior in layered heterogeneous porous media. Analysis of experimental core flood results in composite core systems (the system) along with numerical simulation at the core scale can provide an insight into this problem, especially when the capillary effects are present. In this study unsteady state two phase displacements have been conducted on the system with different internal arrangements. The main contribution is... 

In this research the fluid dynamics characteristics of a stellar turbulent jet flow is studied numerically and the results of three dimensional jet issued from a stellar nozzle are presented. A numerical method based on control volume approach with collocated grid arrangement is employed. The turbulent stresses are approximated using k-ε and k-ω models with four different inlet conditions. The velocity field is presented and the rate of decay at jet centerline is noted. Special attention is drawn on the influence of corner angle and number of wings on mixing in stellar cross section jets. Stellar jets with three; four and five wings and 15-65° corner angles are studied. Also the effect of... 

Recently a great attention has been given to the oscillatory flow modeling in the pulse tube cryocoolers. In this paper multi dimensioning effects of the fluid flow in the pulse tube are investigated. A complete system of governing equations is solved to report the flow field, friction coefficient and Nusselt number in the pulse tube. Harmonic approximation technique is employed to derive an analytical solution. In this respect, mass, momentum and energy balance equations as well as the equation of state for ideal gas are transformed by implementing the harmonic approximation technique. The present model is able to predict the behavior of the two dimensional compressible oscillatory flow in... 

The exergoeconomic analysis is a powerful tool to study an energy system and provide rational decision-making for it. This paper is aimed at exergoeconomic optimization and sensitivity analysis evaluation of the results of a commercial parabolic trough collector (PTC). First, an analysis of optical, thermal, exergy, and economic equations of the PTC system is presented. Then, the objective function and variables are optimized through MATLAB software using the hybrid algorithm code. The objective function as the exergy loss rate is a combination of exergy loss and system cost. The evaluation of the results has been carried out considering the radiation intensity in different months of the... 

The aim of this research is to design an implantable integrated microfluidic system in order to regularly measure the glucose level in the human body, nonenzymatically, using the microdialysis method. The main compartments of this system are a micropump, array of hollow microneedles and an electrochemical sensor. At the base of the microneedles, there are located semipermeable membranes, that when the pumped dialysis fluid passes over them, the glucose of the interstitial fluid diffuses into the dialysis fluid and then, in the sensor section, it is measured nonenzymatically using the amperometry method. Both the arrangement of the miconeedles and the amount of the dialysis fluid flow are... 

Purpose: This paper aims to to simulate the flow and heat transfer during free convection in a square cavity using double-multi-relaxation time (MRT) lattice Boltzmann method. Design/methodology/approach: The double-MRT lattice Boltzmann method is used, and the natural convection fluid flow and heat transfer under influence of different parameters are analyzed. The D2Q5 model and D2Q9 model are used for simulation of temperature field and flow field, respectively. The cavity is filled with CuO-water nanofluid; in addition, the thermo-physical properties of nanofluid and the effect of nanoparticles’ shapes are considered using Koo–Kleinstreuer–Li (KKL) model. On the other hand, the cavity is... 

Hybrid FVM-LBM schemes are developed in the past few years to use capabilities of both Navier-Stokes based finite volume method (FVM) and lattice Boltzmann method (LBM) to solve macro-meso multiscale problems. In this scheme, the major task is to develop some lifting relations that reconstruct distribution functions in LBM sub-domain from macroscopic variables and their derivatives. The macroscopic variables are computed using Navier-Stokes based FVM in macroscale sub-domain, while distribution functions are computed using LBM in mesoscale sub-domain. The pioneer works in this area used the single relaxation time (SRT) version of LBM. However, it is known that the numerical stability and... 

Scale precipitation due to the mixing of incompatible injected water with formation brine and its subsequent deposition in porous media is an unpleasant phenomenon in water injection projects that can lead to severe injectivity and productivity decline. As a result of the complexity of geochemical reactions, modelling scale precipitation and deposition is a challenge. This paper presents a coupled geochemical and fluid flow model to simulate reactive flow in porous media which models pressure difference increase resulting from scale formation during water injection into porous media. To simulate chemical reactions during scale formation and subsequent rock permeability decline, PHREEQC... 

Recently, Colloidal Gas Aphron (CGA) based fluids have been introduced to further develop depleted hydrocarbon reservoirs. This fluid system has been employed in an attempt to control drilling fluid invasion and, thus, reducing formation damage occurred during drilling operations. Understanding the mechanisms of fluid invasion control is of great importance for successful design and application of CGA-based fluids in drilling operations. Although fluid flow of conventional foams has been studied extensively in the available literature, little attention has been paid to CGA fluids flow, especially in heterogeneous fractured porous media. Here, an experimental study was conducted to achieve... 

In this article, effects of magnetic fields induced by a finite length solenoid on the forced-convection heat transfer in a pipe partially filled with porous medium have been investigated. In this regard, two-dimensional steady-state fluid flow in the pipe was considered and the Darcy–Brinkman equation of motion was applied to model the fluid flow in the porous medium, as well as the thermal equilibrium was assumed between the solid phase and the magnetic nanofluid. Effects of electric current passing through the solenoid and the solenoid dimensions (i.e.; diameter and length) on the forced-convection heat transfer were studied carefully. The combined effects of the magnetic field and the... 

In the last decade, extensive attention is devoted to intelligibly designed materials of macro/micro-structures containing the fluid flow. In this study, intelligent control and vibrational stability of cantilevered fluid conveying macro/micro-tubes utilizing axially functionally graded (AFG) materials are considered. The governing equation of motion of the system is derived based on modified couple stress theory and then is discretized using Galerkin method. A detailed investigation is carried out to elaborate the influence of various parameters such as material properties, axial compressive load, and Pasternak foundation on the dynamical behavior of the system, all of which are influential... 

This study describes a 1-D code, which determines the one-dimensional flow and heat transfer distributions in arbitrarily connected flow passages with multiple inlets and outlets. The procedure uses a component solver, which solves the one-dimensional compressible fluid flow and heat transfer equations inside an individual cooling passage. Also, it uses experimental correlations for the heat transfer coefficient and friction factor for each cooling passage. In addition to the component solver, there is a flow network solver subroutine, which applies the mass and energy conservation equations properly at each internal node. In order to validate this 1-D code, both the component and the flow... 

This study describes a 1-D code, which determines the one-dimensional flow and heat transfer distributions in arbitrarily connected flow passages with multiple inlets and outlets. The procedure uses a component solver, which solves the one-dimensional compressible fluid flow and heat transfer equations inside an individual cooling passage. Also, it uses experimental correlations for the heat transfer coefficient and friction factor for each cooling passage. In addition to the component solver, there is a flow network solver subroutine, which applies the mass and energy conservation equations properly at each internal node. In order to validate this 1-D code, both the component and the flow... 

Acidizing is one of the most effective techniques to remove the formation damage and restore (or even increase) the permeability of the near wellbore region. Although this technique is widely used to resolve the skin problem, it could initiate new damages itself that hinder the fluid flow and decrease the well production, consequently. Acid-oil emulsion and sludge formation are known as two major induced formation damage and the main reasons for the oil well acid treatment failures. Despite its critical effects, no comprehensive study has been addressed this specific type of formation damages in details. In this study, the acid-oil emulsion and asphaltic sludge formation were evaluated... 

Capillary imbibition is an important recovery mechanism in naturally fractured reservoirs when water-filled fractures surround water-wet matrix blocks. A large amount of studies of imbibition process is simply total or partial immersion of nonwetting phase saturated rock in aqueous wetting phase. However, water advance in fractures during water flooding or water encroachment from an active aquifer introduces time dependent boundary conditions where invariant exposure of rock surface to water is not representative. In this work, a laboratory simulated matrix-fracture system was used to investigate different aspects of imbibition in the presence of fracture fluid flow (namely dynamic... 

A new characteristic-based method is developed and used for solving the mixed and forced convection problems. The nano-fluid flow with heat transfer is simulated with a novel characteristic-based scheme in closed domains with different aspect ratios. For this purpose, a FORTRAN code has been written and developed. Water as a pure fluid and water-titanium dioxide as a nano-fluid were considered. The governing equations are solved by the finite volume utilizing a characteristic-based scheme for the convective fluxes. The simulation is done at Grashof numbers from 100 to 104, Reynolds numbers from 100 to 1000, and volume fractions of nano-particles from 0% to 10%. Streamlines, isotherms,... 

In this paper, the stability of pipes conveying fluid with viscoelastic fractional foundation is investigated. The pipe is fixed at the beginning while the pipe end is constrained with two lateral and rotational springs. The fluid flow effect is modeled as a lateral distributed force, containing the fluid inertia, Coriolis and centrifugal forces. The pipe is modeled using the Euler-Bernoulli beam theory and a fractional Kelvin-Voigt model is employed to describe the viscoelastic foundation. The equation of motion is derived using the extended Hamilton's principle. Presenting the derived equation in Laplace domain and applying the Galerkin method, a set of algebraic equations is extracted....