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Experimental Investigation of Formability and Mechanical Properties of Composites Manufactured by Direct Roll Bonding
, M.Sc. Thesis Sharif University of Technology ; Akbarzadeh, Abbas (Supervisor)
Abstract
In this study, the ST14 low carbon steel sheet was used as a skin layer in the construction of three-layer laminates. The use of this steel was due to its high mechanical properties and excellent formability. A thermoplastic polyurethane sheet was also used as the core layer. The selection criteria of this polymer were no need for adhesive (for bonding metal to polymer) as well as proper mechanical properties (elongation and strength) and physical (density). The perfect process for manufacturing three-layer laminates is the roll bonding process. To manufacturing a laminate with the desired properties of the designer, the rolling parameters (rolling speed and thickness reduction) must be...
Fabrication and Investigation of the Microscopic Structure and Mechanical Properties of Zx00 Magnesium Alloy by Applying the Multi-Directional Forging Process on Extruded and Homogenized Samples
, M.Sc. Thesis Sharif University of Technology ; Akbarzadeh, Abbas (Supervisor)
Abstract
Magnesium and its alloys have gained significant attention in medical applications due to their good biocompatibility. However, their widespread use has been limited by some inherent drawbacks, such as poor mechanical properties. The ZX00 magnesium alloy has been used in medical applications, including implants, due to its slow degradation rate and good ossification. However, this alloy lacks sufficient strength and ductility. The severe plastic deformation method can create an ultrafine grain structure and improve mechanical properties. In this study, to improve the mechanical properties and create an ultrafine grain structure, the multi-directional forging process was performed on...
Size dependence and effect of potential parameters on properties of nano-cavities in liquid xenon using molecular dynamics simulation
, Article Chemical Physics ; Volume 381, Issue 1-3 , March , 2011 , Pages 44-48 ; 03010104 (ISSN) ; Abroshan, H ; Taherkhani, F ; Izanloo, C ; Parsafar, G. A ; Sharif University of Technology
2011
Abstract
We have investigated the size dependence of a nano-cavity properties produced in a Xe fluid using molecular dynamics simulations. We have created a nano-cavity of different sizes at 170 and 200 K (cavities diameters are within 1-10 nm). Liquid pressure, vapor pressure and surface tension of the nano-cavity for some given values of diameter are calculated. Within 1-10 nm cavity diameter, we have observed two opposite behavior for dependency of surface tension on the cavity diameter: for the range of 1-5 nm, it increases with the diameter, while, for the range of 5-10 nm remains constant. Also, the value of liquid pressure becomes less negative, when the size of cavity increases. Vapor...
A lightweight hierarchical authentication scheme for internet of things
, Article Journal of Ambient Intelligence and Humanized Computing ; Volume 10, Issue 7 , 2019 , Pages 2607-2619 ; 18685137 (ISSN) ; Bayat, M ; Zahednejad, B ; Payandeh, A ; Aref, M. R ; Sharif University of Technology
Springer Verlag
2019
Abstract
The Internet of Things (IoT) technology enables numerous things with different processing power and storage capacity to communicate and share data with each other. Considering the constrained devices of the IoT network in terms of processing and storage, designing a lightweight authentication scheme is quite important. So in this paper, we propose a lightweight authentication scheme based on Chebyshev Chaotic Maps. In the proposed scheme we apply a hierarchical structure to define different access controls for various entities. We then provide a formal analysis via the BAN logic to show the security of our scheme. Moreover, we compare our proposed scheme with previous ones in terms of...
The role of polyethylene glycol size in chemical spectra, cytotoxicity, and release of pegylated nanoliposomal cisplatin
, Article Assay and Drug Development Technologies ; Volume 17, Issue 5 , 2019 , Pages 231-239 ; 1540658X (ISSN) ; Jamehbozorgi, S ; Akbarzadeh, I ; Aghabozorg, H. R ; Amini, A ; Sharif University of Technology
Mary Ann Liebert Inc
2019
Abstract
This study aimed to synthesize methoxy polyethylene glycol propionaldehyde (mPEG20,000-ALD) for the preparation of PEGylated nanoliposomal cisplatin. Nanocarriers such as liposomes are developed for a wide range of drug delivery systems. PEG with high molecular weight (Mw) is used to coat the liposomes. In this study, simulated Fourier transform infrared (FTIR) spectra of mPEG-ALD were obtained using density functional theory (DFT) calculations and then compared with actual FTIR spectrum of mPEG20,000-ALD (Mw = 20 kDa). We found that the intensity of C = O stretching vibration at 1,700 cm-1 related to the carbonyl functional group of mPEG20,000-ALD was very weak. The results of DFT...
A lightweight hierarchical authentication scheme for internet of things
, Article Journal of Ambient Intelligence and Humanized Computing ; 2018 , Pages 1-13 ; 18685137 (ISSN) ; Bayat, M ; Zahednejad, B ; Payandeh, A ; Aref, M. R ; Sharif University of Technology
Springer Verlag
2018
Abstract
The Internet of Things (IoT) technology enables numerous things with different processing power and storage capacity to communicate and share data with each other. Considering the constrained devices of the IoT network in terms of processing and storage, designing a lightweight authentication scheme is quite important. So in this paper, we propose a lightweight authentication scheme based on Chebyshev Chaotic Maps. In the proposed scheme we apply a hierarchical structure to define different access controls for various entities. We then provide a formal analysis via the BAN logic to show the security of our scheme. Moreover, we compare our proposed scheme with previous ones in terms of...
Traffic-load-aware virtual channel power-gating in network-on-chips
, Article Advances in Computers ; 2021 ; 00652458 (ISSN) ; Mirhosseini, A ; Akbarzadeh, N ; Modarressi, M ; Sarbazi Azad, H ; Sharif University of Technology
Academic Press Inc
2021
Abstract
Network-on-Chips (NoCs) employ several virtual channels per input port to mitigate head-of-line blocking issue in transmitting network packets. Unfortunately, these virtual channels are power-hungry resources that significantly contribute to the total power consumption of NoCs. In particular, we make the key observation that even in high load traffic, a number of virtual channels are idle, imposing significant static power overhead. Prior works use power-gating technique to switch off idle VCs and reduce the static power consumption. However, we observe that prior works are mostly suitable for low traffic loads and are ineffective in high traffic loads. In this chapter, we aim to propose a...
An efficient DVS scheme for on-chip networks
, Article Advances in Computers ; 2021 ; 00652458 (ISSN) ; Mirhosseini, A ; Akbarzadeh, N ; Aghilinasab, H ; Sarbazi Azad, H ; Sharif University of Technology
Academic Press Inc
2021
Abstract
Network-on-Chips (NoCs) consume a significant portion of multiprocessors' total power. Dynamic Voltage Scaling (DVS) which can reduce both static and dynamic power consumption is widely applied to NoCs. However, prior DVS schemes usually impose significant performance overhead to NoCs as NoCs need to work with lower clock frequencies when the supply voltage is scaled down. In this chapter, we propose a novel DVS scheme for NoCs with no performance overhead. We reduce power consumption when there is few Virtual Channels (VCs) that have active allocation requests at each cycle compared to the total number of available VCs. To enable multiple latencies with different slack times, we propose a...
Traffic-load-aware virtual channel power-gating in network-on-chips
, Article Advances in Computers ; Volume 124 , 2022 , Pages 1-19 ; 00652458 (ISSN); 9780323856881 (ISBN) ; Mirhosseini, A ; Akbarzadeh, N ; Modarressi, M ; Sarbazi Azad, H ; Sharif University of Technology
Academic Press Inc
2022
Abstract
Network-on-Chips (NoCs) employ several virtual channels per input port to mitigate head-of-line blocking issue in transmitting network packets. Unfortunately, these virtual channels are power-hungry resources that significantly contribute to the total power consumption of NoCs. In particular, we make the key observation that even in high load traffic, a number of virtual channels are idle, imposing significant static power overhead. Prior works use power-gating technique to switch off idle VCs and reduce the static power consumption. However, we observe that prior works are mostly suitable for low traffic loads and are ineffective in high traffic loads. In this chapter, we aim to propose a...
An efficient DVS scheme for on-chip networks
, Article Advances in Computers ; Volume 124 , 2022 , Pages 21-43 ; 00652458 (ISSN); 9780323856881 (ISBN) ; Mirhosseini, A ; Akbarzadeh, N ; Aghilinasab, H ; Sarbazi Azad, H ; Sharif University of Technology
Academic Press Inc
2022
Abstract
Network-on-Chips (NoCs) consume a significant portion of multiprocessors' total power. Dynamic Voltage Scaling (DVS) which can reduce both static and dynamic power consumption is widely applied to NoCs. However, prior DVS schemes usually impose significant performance overhead to NoCs as NoCs need to work with lower clock frequencies when the supply voltage is scaled down. In this chapter, we propose a novel DVS scheme for NoCs with no performance overhead. We reduce power consumption when there is few Virtual Channels (VCs) that have active allocation requests at each cycle compared to the total number of available VCs. To enable multiple latencies with different slack times, we propose a...
Targeted nanomedicines for the treatment of bone disease and regeneration
, Article Medicinal Research Reviews ; 2020 ; Zandi, N ; Mazaheri, M ; Luther, G. A ; Ghovvati, M ; Akbarzadeh, A ; Annabi, N ; Sharif University of Technology
John Wiley and Sons Inc
2020
Abstract
Targeted delivery by either passive or active targeting of therapeutics to the bone is an attractive treatment for various bone related diseases such as osteoporosis, osteosarcoma, multiple myeloma, and metastatic bone tumors. Engineering novel drug delivery carriers can increase therapeutic efficacy and minimize the risk of side effects. Developmnet of nanocarrier delivery systems is an interesting field of ongoing studies with opportunities to provide more effective therapies. In addition, preclinical nanomedicine research can open new opportunities for preclinical bone-targeted drug delivery; nevertheless, further research is needed to progress these therapies towards clinical...
Targeted nanomedicines for the treatment of bone disease and regeneration
, Article Medicinal Research Reviews ; Volume 41, Issue 3 , 2021 , Pages 1221-1254 ; 01986325 (ISSN) ; Zandi, N ; Mazaheri, M ; Luther, G. A ; Ghovvati, M ; Akbarzadeh, A ; Annabi, N ; Sharif University of Technology
John Wiley and Sons Inc
2021
Abstract
Targeted delivery by either passive or active targeting of therapeutics to the bone is an attractive treatment for various bone related diseases such as osteoporosis, osteosarcoma, multiple myeloma, and metastatic bone tumors. Engineering novel drug delivery carriers can increase therapeutic efficacy and minimize the risk of side effects. Developmnet of nanocarrier delivery systems is an interesting field of ongoing studies with opportunities to provide more effective therapies. In addition, preclinical nanomedicine research can open new opportunities for preclinical bone-targeted drug delivery; nevertheless, further research is needed to progress these therapies towards clinical...
On the existence of an analytic solution to the 1-D Ising model with nearest and next-nearest neighbor interactions in the presence of a magnetic field
, Article Phase Transitions ; Volume 84, Issue 1 , Dec , 2011 , Pages 77-84 ; 01411594 (ISSN) ; Daryaei, E ; Abroshan, H ; Akbarzadeh, H ; Parsafar, G ; Fortunelli, A ; Sharif University of Technology
2011
Abstract
To solve the controversy, regarding the existence of an analytic solution to the 1-D Ising model with nearest-neighbor (NN) and next-nearest-neighbor (NNN) interactions in the presence of a magnetic field, we apply the transfer matrix method to solve the 1-D Ising model in the presence of a magnetic field, taking both NN and NNN interactions into account. We show that it is possible to write a transfer matrix only if the number of sites is even. Even in such a case, it is impossible to diagonalize the transfer matrix in an analytic form. Therefore, we employ a numerical method to obtain the eigenvalues of the transfer matrix. Moreover, the heat capacity, magnetization, and magnetic...
Investigation of hydrodynamically dominated membrane rupture, using smoothed particle hydrodynamics–finite element method
, Article Fluids ; Volume 4, Issue 3 , 2019 ; 23115521 (ISSN) ; Taeibi Rahni, M ; Akbarzadeh, A. M ; Javadi, K ; Ahmadi, G ; Sharif University of Technology
MDPI AG
2019
Abstract
The rupturing process of a membrane, located between two fluids at the center of a three-dimensional channel, is numerically investigated. The smoothed particle hydrodynamics (SPH) and the finite element method (FEM) are used, respectively, for modeling the fluid and solid phases. A range of pressure differences and membrane thicknesses are studied and two different rupturing processes are identified. These processes differ in the time scale of the rupture, the location of the rupture initiation, the level of destruction and the driving mechanism. © 2019 by the authors
Apoptosis induction, cell cycle arrest and anti-cancer potential of tamoxifen-curcumin loaded niosomes against MCF-7 cancer cells
, Article Iranian Journal of Pathology ; Volume 17, Issue 2 , 2022 , Pages 183-190 ; 17355303 (ISSN) ; Tafvizi, F ; Shamsi, F ; Amiri, S ; Farajzadeh, A ; Akbarzadeh, I ; Sharif University of Technology
Iranian Society of Pathology
2022
Abstract
Background & Objective: Breast cancer is the most common cancer among women. One of the most effective treatments for breast cancer is chemotherapy, in which specific drugs destroy the mass and its proliferation is inhibited. Chemotherapy is the most effective adjunctive therapy when multiple medications are used concurrently. Also, combining the drugs with nanocarrier has become an important strategy in targeted therapy. This study is designed to assess the apoptosis induction, cell cycle arrest, and anti-cancer potential of Tamoxifen-Curcumin-loaded niosomes against MCF-7 Cancer Cells. Methods: A novel niosomal formulation of tamoxifen-curcumin with Span 80 and lipid to drug ratio of 20...
Texture and Microstructure of Ultra Fine Grained Structure Produced by Accumulative Roll Bonding (ARB) and Warm Rolling Processes in an IF Steel
, Ph.D. Dissertation Sharif University of Technology ; Akbarzadeh, Abbas (Supervisor)
Abstract
Accumulative Roll Bonding (ARB) process has been developed during last decade to produce the Ultra Fine Grained (UFG) structures with high strength. In the present study, a Ti-IF steel was deformed up to equivalent strain of 4.8 at 500 ˚C using ARB process. For comparing the ARB with conventional forming processes, some samples were deformed with similar equivalent strain to ARB conditions at 500 ˚C and 300 ˚C as warm rolling. Moreover, the thermo-mechanical warm rolling was simulated by warm torsion. The ARB and warm rolled samples with largest strains were annealed at 750 ˚C. The microstructure and texture were studied using Electron Back Scattered Diffraction (EBSD) method. The...
Effect of Cold Rolling and Intercritical Annealing Temperature of TRIP Steel Sheet on Martensitic Transtormation during Retained Austenite Deformation
, M.Sc. Thesis Sharif University of Technology ; Akbarzadeh, Abbas (Supervisor)
Abstract
TRIP steel with good plasticity properties, has ferrite, bainite and retained austenite phases at ambient temperature. According to austenite to martensite phase transformation during plastic deformation, this grade of steel has high elongation and ultimate tensile strength, simultaneously. There are some parameters which affect the stability of retained austenite, such as: imposed strain, strain rate, temperature of deformation, grain size, weight percentage of different alloy elements and crystallographic orientation of existing phases. Mechanical properties of TRIP steels are improved by increasing stability of retained austenite. TRIP steels have been...
Numerical Investigation of Dewetting of Evaporating thin Films over Nanometric Topography
, M.Sc. Thesis Sharif University of Technology ; Moosavi, Ali (Supervisor)
Abstract
Evaporation and condensation of thin films can rupture or stabilize thin film .We show that evaporation hastens dewetting of a thin film. Dewetting over nanometric downward step causes pinning of the contact line near the step. This phenomena is not permanent and after certain time that contact angle reaches to its critical value depinnnig happens. We also study the effect of the step size, contact angle, film thickness, slip and evaporation on the depinning time of the contact line. We show that depinnig time has a reverse relation with the rate of evaporation
Pt–NiO–Al2O3/G derived from graphene-supported layered double hydroxide as efficient catalyst for p-nitrophenol reduction
, Article Research on Chemical Intermediates ; Volume 43, Issue 10 , 2017 , Pages 5829-5839 ; 09226168 (ISSN) ; Gholami, M. R ; Sharif University of Technology
2017
Abstract
The present work reports the synthesis of a Pt-modified NiO–Al2O3 nanocomposite derived from graphene-supported layered double hydroxide (Pt–NiO/G) and demonstrates its catalytic activity. The resulting Pt–NiO/G nanocomposite was characterized by FT-IR, XRD, FE-SEM, TEM and XPS techniques and used for catalytic reduction of p-nitrophenol (P-NP) to p-aminophenol (P-AP). The influence of graphene on catalytic activity was comparatively considered by preparation of Pt–NiO nanoparticles derived from layered double hydroxide. The superior catalytic performance of Pt–NiO/G was ascribed to the synergistic effect between Pt and NiO. Furthermore, reduction of P-NP was considered to follow a...
Cardiac contraction motion compensation in gated myocardial perfusion SPECT: a comparative study
, Article Physica Medica ; Volume 49 , 2018 , Pages 77-82 ; 11201797 (ISSN) ; Rahmim, A ; Fatemizadeh, E ; Akbarzadeh, A ; Farahani, M. H ; Farzanefar, S ; Ay, M. R ; Sharif University of Technology
Associazione Italiana di Fisica Medica
2018
Abstract
Introduction: Cardiac contraction significantly degrades quality and quantitative accuracy of gated myocardial perfusion SPECT (MPS) images. In this study, we aimed to explore different techniques in motion-compensated temporal processing of MPS images and their impact on image quality and quantitative accuracy. Material and method: 50 patients without known heart condition underwent gated MPS. 3D motion compensation methods using Motion Freezing by Cedars Sinai (MF), Log-domain Diffeomorphic Demons (LDD) and Free-Form Deformation (FFD) were applied to warp all image phases to fit the end-diastolic (ED) phase. Afterwards, myocardial wall thickness, myocardial to blood pool contrast, and...