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    , M.Sc. Thesis Sharif University of Technology Mohammad Alippour Ahari, Roua (Author) ; Eshghi, Koorosh (Supervisor)
    Abstract
    The focus of this research is to present a model to verify the acceptance of projects with time and cost dependency on the usage of equipments. Decision on these projects is based on a dynamic programming in which at each stage, the profit of available projects in this stage, equipment value and the best choice of future stage are decision keys. In other words, after the completion of a project, it should be decided between doing a project or selling the equipment and leaving the remaining projects. For each projects, there is a product network that includes projects jobs and operations. After accepting projects, equipments of the projects will not be renewed and the usage of the equipments... 

    Nonlinear Performance of 3-D Steel Structures by Scaled Nonlinear Dynamic Procedure

    , M.Sc. Thesis Sharif University of Technology Hashemian, Behdad (Author) ; Mofid, Masoud (Supervisor)
    Abstract
    It is well known that the most rigorous method to assess the performance and to predict the seismic demands of a structure subjected to earthquake is nonlinear time history analysis. However, this technique is accompanied by complexities and difficulties in evaluating the seismic demands of structures and requires superior knowledge and skill. As a result, in recent years, nonlinear static analysis has been proposed in performance based design procedures. One of the primary assumptions of nonlinear static procedures is that the behavior of a structure with multiple degrees of freedom (MDOF) subjected to seismic ground motion can be estimated from the response of an oscillator with a single... 

    A Meta-Heuristic Approach for a Special Class of Job Shop Scheduling Problem

    , M.Sc. Thesis Sharif University of Technology Behroozi, Mehdi (Author) ; Koorosh, Eshghi (Supervisor)
    Abstract
    The job shop scheduling problem is an important and applicable optimization problem and has been attracted by many researchers in recent decades. A huge amount of applications of job shop scheduling problem in industries and services has been found yet. During the last decade, the sequence dependent setup time constraint has been considered in many researches, but with respect to the knowledge of authors, very few of these researches have considered the inseparable setup. Furthermore, few of them have considered the release date assumption. In this thesis, the classical job shop scheduling problem and the inseparable sequence dependent setup time and release date constrained problem have... 

    Development of an Integrated Solar Energy System for a Typical Educational Building

    , M.Sc. Thesis Sharif University of Technology Motavaselian, Ali Mohammad (Author) ; Saboohi, Yadollah (Supervisor)
    Abstract
    In the present thesis, A Computer software has been developed to evaluate technical and economic aspects of photovoltaic systems, off-grid and on-grid configuration, in urban areas where the electricity grid is accessible. As a case study the building of Energy Engineering faculty with annual demand of electricity in lighting section equals to 80048 kWh was considered. Regarding incident radiation and PV system characteristics with the aid of utilizability concept, a technical evaluation has been performed then life-cycle saving index was considered as a criterion for choosing an optimum nominal size of the system. Results show that for current electricity tariff of educational buildings ... 

    Design and Modeling of a Solar Combined Cooling, Heating and Power System and it’s Validation with Empirical Results

    , M.Sc. Thesis Sharif University of Technology Yassaghi, Hamed (Author) ; Saboohi, Yadollah (Supervisor)
    Abstract
    Due to the growth of energy consumption the use of new technologies and efficient energy conversion is necessary. An example of efficient energy conversion technology is CCHP (Combined Cooling, Heating and Power). The aim of the present research work is to develop a model that could be applied for optimal design of a hybrid CCHP system which would be Solar Combined Cooling, Heating and Power (SCCHP). In order to do so,microturbine power system, cooling and heating equipment’s such as absorption system and heat exchanger and also solar collector have been considered as an integral part of the system. The objective of the application of the model has been to identify proper sizing of all... 

    A Train Sequencing and Stop Scheduling Model inDouble Track Railway Lines by hHybrid GRASP-VNS Meta-Heuristic

    , M.Sc. Thesis Sharif University of Technology Hassannayebi, Erfan (Author) ; Kianfar, Fereydoon (Supervisor)
    Abstract
    The train scheduling problem is one of the most important scheduling problems in the transportation systems. The goal of train scheduling problem is generating a feasible timetable which consists of train departure times and determining the best station to stop. Optimizing the railway capacity is one of the most important goals in train scheduling phase. The sequence of dispatching trains and stopping schedule are the main factors that can affect railway capacity on double track lines. In this thesis, a double-track train sequencing problem is studied in order to maximize the railway capacity, subject to a set of operational requirements. This research proposes a flexible flow shop... 

    Modeling of the Flexible Instrument Inside the Vascular Environment for Its Motion Control in Minimally Invasive Procedures

    , M.Sc. Thesis Sharif University of Technology Rezazadeh, Taha (Author) ; Nejat Pishkenari, Hossein (Supervisor)
    Abstract
    Minimally invasive procedures are diagnostic or therapeutic methods that cause minimal injuries and side effects for patients. PCI is a common minimally invasive procedure for diagnosis and curing of cardiovascular disorders. In this procedure, the surgeon can have access to the cardiac vessels by a flexible instrument. However, motion control of this instrument inside the patient's body relies on surgeon's skills and in some cases, is time consuming so that the toxic effects of radiation on patient and surgical team increases. Magnetic flexible instruments are suggested to address this problem. Nevertheless, motion control of the flexible instrument inside the body still has many challenges... 

    Design and Implementation of an Auto-Grasping Algorithm for a Robotic Laparoscopic Instrument

    , M.Sc. Thesis Sharif University of Technology Amirkhani, Golchehr (Author) ; Farahmand, Farzam (Supervisor)
    Abstract
    The main goal of this project is to design and implementation of the tissue auto-grasping algorithm for a wristed laparoscopic instrument. In this algorithm, the difference between the pinch forces of two jaws was taken into account when the pull force direction corresponding to the rod instrument direction was changed. The term ‘Tissue auto-grasping’ means automatic adjustment of the pinch force corresponding to the pull force exerted on the tissue by the robotic surgical instrument, so that slip and exerting excessive force on the tissue are prevented. In this study, obtaining the pinch force is based on the proximal force-sensing technique. For this reason, the force model of wristed... 

    Development of Transient Model of Fuel Consumption to Optimize IVT

    , M.Sc. Thesis Sharif University of Technology Ebadi, Mohammad (Author) ; Saadat Foumani, Mahmoud (Supervisor) ; Kazemzade Hannani, Siamak (Co-Advisor)
    Abstract
    Changes in the internal structure of engines for reducing fuel consumption has almost stopped. While changes in powertrain is a better way to reduce vehicle fuel consumption. Recently, infinitely variable transmissions or IVTs have attracted large attention of car manufacturers . In these systems, due to the continuous transmission ratio, engine speed is kept in a range which is the optimum fuel consumption speed range. Designing of these systems for each vehicle must be done according to the requirements of the vehicle and engine abilities. So, an exact model of engine fuel consumption for the design of these systems is required. One way of improving the accuracy of conventional models, is... 

    Investigation of cervical spine curvature in females with postural neck pain

    , Article Journal of Zanjan University of Medical Sciences and Health Services ; Volume 25, Issue 110 , 2017 , Pages 110-119 ; 16069366 (ISSN) Salahzadeh, Z ; Maroufi, N ; Ahmadi, A ; Behtash, H ; Hazhir Sahneh, S ; Parnianpour, M ; Sharif University of Technology
    Zanjan University of Medical Sciences and Health Services  2017
    Abstract
    Background and Objective: Changes in the cervical spine curvature leads to increased shear force and compression stress on cervical spine and axial loading in different cervical segments. The objective of this study was to compare the general and segmental curvature in the upper and lower cervical spine of women with postural neck pain and Forward Head Posture (FHP), women without neck pain but with FHP and healthy women. Material and Methods: 45 women were divided into three groups: 15 women with postural neck pain and FHP, 15 women without neck pain but with FHP and 15 healthy women. Photography was used to assess neck posture while cervical spine curvature was measured using fluoroscopy... 

    Kinetics of swelling of cylindrical temperature-responsive hydrogel: a semi-analytical study

    , Article International Journal of Applied Mechanics ; Volume 12, Issue 8 , 2020 Namdar, A. H ; Mazaheri, H ; Sharif University of Technology
    World Scientific  2020
    Abstract
    Cylindrical hydrogels have a wide variety of applications, especially in microfluidics as micro-valves, micro-mixers, and micro-lenses. Main advantages of them can be mentioned as their simple geometry and autonomous functionality due to their responses to the environmental stimuli. In current research, kinetics of swelling, shrinking and force generation of cylindrical temperature-responsive hydrogels have been investigated analytically. According to this, models of fluid permeation and large deformation of the hydrogels were considered and an analytical solution was performed. In order to study the behavior of the cylindrical hydrogels, the temperature is changed between higher and lower... 

    Automated analysis of karyotype images

    , Article Journal of Bioinformatics and Computational Biology ; Volume 20, Issue 3 , 2022 ; 02197200 (ISSN) Khazaei, E ; Emrany, A ; Tavassolipour, M ; Mahjoubi, F ; Ebrahimi, A ; Motahari, S. A ; Sharif University of Technology
    World Scientific  2022
    Abstract
    Karyotype is a genetic test that is used for detection of chromosomal defects. In a karyotype test, an image is captured from chromosomes during the cell division. The captured images are then analyzed by cytogeneticists in order to detect possible chromosomal defects. In this paper, we have proposed an automated pipeline for analysis of karyotype images. There are three main steps for karyotype image analysis: image enhancement, image segmentation and chromosome classification. In this paper, we have proposed a novel chromosome segmentation algorithm to decompose overlapped chromosomes. We have also proposed a CNN-based classifier which outperforms all the existing classifiers. Our... 

    Advances in skin regeneration: application of electrospun scaffolds

    , Article Advanced Healthcare Materials ; Volume 4, Issue 8 , 2015 , Pages 1114-1133 ; 21922640 (ISSN) Norouzi, M ; Boroujeni, S. M ; Omidvarkordshouli, N ; Soleimani, M ; Sharif University of Technology
    Wiley-VCH Verlag  2015
    Abstract
    The paucity of cellular and molecular signals essential for normal wound healing makes severe dermatological ulcers stubborn to heal. The novel strategies of skin regenerative treatments are focused on the development of biologically responsive scaffolds accompanied by cells and multiple biomolecules resembling structural and biochemical cues of the natural extracellular matrix (ECM). Electrospun nanofibrous scaffolds provide similar architecture to the ECM leading to enhancement of cell adhesion, proliferation, migration and neo tissue formation. This Review surveys the application of biocompatible natural, synthetic and composite polymers to fabricate electrospun scaffolds as skin... 

    Electrospun superhydrophobic polystyrene hollow fiber as a probe for liquid–liquid microextraction with gas chromatography-mass spectrometry

    , Article Journal of Separation Science ; Volume 39, Issue 19 , 2016 , Pages 3782-3788 ; 16159306 (ISSN) Bagheri, H ; Baktash, M. Y ; Jahandar, K ; Sharif University of Technology
    Wiley-VCH Verlag  2016
    Abstract
    A superhydrophobic polystyrene hollow fiber was electrospun around a copper spring collector. This approach led to the construction of a hollow fiber membrane, and the copper spring acted as a scaffold. The characteristic properties of the hollow fiber were studied by scanning electron microscopy. The membrane was used as a probe to transfer the extracting solvent from aquatic media to a gas chromatograph. After performing the liquid–liquid microextraction procedure on 10 mL of water sample by octanol, the whole solution was passed through the prepared polystyrene hollow fiber. Propanol, containing 2 mg/L lindane as the internal standard, was used for desorption and an aliquot of 2 μL of the... 

    Chemometrics comparison of gas chromatography with mass spectrometry and comprehensive two-dimensional gas chromatography with time-of-flight mass spectrometry Daphnia magna metabolic profiles exposed to salinity

    , Article Journal of Separation Science ; Volume 41, Issue 11 , 2018 , Pages 2368-2379 ; 16159306 (ISSN) Parastar, H ; Garreta Lara, E ; Campos, B ; Barata, C ; Lacorte, S ; Tauler, R ; Sharif University of Technology
    Wiley-VCH Verlag  2018
    Abstract
    The performances of gas chromatography with mass spectrometry and of comprehensive two-dimensional gas chromatography with time-of-flight mass spectrometry are examined through the comparison of Daphnia magna metabolic profiles. Gas chromatography with mass spectrometry and comprehensive two-dimensional gas chromatography with mass spectrometry were used to compare the concentration changes of metabolites under saline conditions. In this regard, a chemometric strategy based on wavelet compression and multivariate curve resolution–alternating least squares is used to compare the performances of gas chromatography with mass spectrometry and comprehensive two-dimensional gas chromatography with... 

    A continuous flow microfluidic device based on contactless dielectrophoresis for bioparticles enrichment

    , Article Electrophoresis ; Volume 39, Issue 3 , 2018 , Pages 445-455 ; 01730835 (ISSN) Rahmani, A ; Mohammadi, A. A ; Kalhor, H. R ; Sharif University of Technology
    Wiley-VCH Verlag  2018
    Abstract
    In recent years, applications of dielectrophoresis-based platforms have been recognized as effective and dependable approach to separate cells and bioparticles, suspended in different carrier fluids, based on particle size and electrical properties. In this study, a microfluidic device was fabricated by an unprecedented electrode pattern, and several experiments were performed to enrich samples including either of yeast, Escherichia coli, or latex particles. A chemical deposition-based method was employed for fabrication of microelectrodes, inducing nonuniform electric field required for dielectrophoresis-based separation. One major advantage of our employed method is low fabrication cost,... 

    Development of multi-response optimization and quadratic calibration curve for determination of ten pesticides in complex sample matrices using QuEChERS dispersive liquid–liquid microextraction followed by gas chromatography

    , Article Journal of Separation Science ; Volume 42, Issue 23 , 2019 , Pages 3553-3562 ; 16159306 (ISSN) Balsini, P ; Parastar, H ; Sharif University of Technology
    Wiley-VCH Verlag  2019
    Abstract
    In this study, QuEChERS combined with dispersive liquid-liquid microextraction is developed for extraction of ten pesticides in complex sample matrices of water and milk. In this regard, effective factors of proposed extraction technique combined with gas chromatography with flame ionization detector were designed, modeled, and optimized using central composite design, multiple linear regression, and Nelder–Mead simplex optimization. Later, univariate calibration model for ten pesticides was developed in concentration range of 0.5–100 ng/mL. Surprisingly, quadratic calibration behavior was observed for some of the pesticides. In this regard, Mandel's test was used for evaluating linearity... 

    Novel microfluidic graphene oxide–protein amperometric biosensor for detecting sulfur compounds

    , Article Biotechnology and Applied Biochemistry ; Volume 66, Issue 3 , 2019 , Pages 353-360 ; 08854513 (ISSN) Ghaemi, A ; Abdi, K ; Javadi, S ; Shehneh, M. Z ; Yazdian, F ; Omidi, M ; Rashedi, H ; Haghiralsadat, B. F ; Asayeshnaeini, O ; Sharif University of Technology
    Wiley-Blackwell Publishing Ltd  2019
    Abstract
    Sulfur compounds are essential for many industries and organisms; however, they cause serious respiratory problems in human beings. Therefore, determination of sulfur concentration is of paramount importance. The research approach in the field of detecting contaminants has led to smaller systems that provide faster and more effective ways for diagnosis purposes. In this study, a novel portable amperometric graphene oxide–protein biosensor platform is investigated. The main characteristic of this structure is the implementation of a microfluidic configuration. With albumin metalloprotein as the biorecognition element, graphene oxide was synthesized and characterized by transmission electron... 

    Improvement of upper limb motor control and function after competitive and noncompetitive volleyball exercises in chronic stroke survivors: a randomized clinical trial

    , Article Archives of Physical Medicine and Rehabilitation ; Volume 100, Issue 3 , 2019 , Pages 401-411 ; 00039993 (ISSN) Mandehgary Najafabadi, M ; Azad, A ; Mehdizadeh, H ; Behzadipour, S ; Fakhar, M ; Taghavi Azar Sharabiani, P ; Parnianpour, M ; Taghizadeh, G ; Khalaf, K ; Sharif University of Technology
    W.B. Saunders  2019
    Abstract
    Objectives: To investigate the effects of competitive and noncompetitive volleyball exercises on the functional performance and motor control of the upper limbs in chronic stroke survivors. Design: Randomized clinical trial. Setting: Outpatient rehabilitation center. Participants: Chronic stroke survivors (N=48). Interventions: Participants were randomly assigned to competitive (n=16) or noncompetitive (n=16) volleyball exercise groups (60min/d volleyball exercise+30min/d traditional rehabilitation, 3d/wk for 7wk) and control group (n=16). Main Outcome Measures: Reach and grasp motor control measures were evaluated through kinematic analysis. Functional outcomes were assessed via Motor... 

    Effect of microthread design of dental implants on stress and strain patterns: A three-dimensional finite element analysis

    , Article Biomedizinische Technik ; Volume 58, Issue 5 , September , 2013 , Pages 457-467 ; 00135585 (ISSN) Amid, R ; Raoofi, S ; Kadkhodazadeh, M ; Movahhedi, M. R ; Khademi, M ; Sharif University of Technology
    Walter de Gruyter and Co  2013
    Abstract
    The aim of this study was to use finite element analysis (FEA) to assess the influence of microthread design at the implant neck on stress distribution in the surrounding bone. A commercially available implant with 3.5 mm diameter and 10.5 mm length was selected and used as a model. For the purpose of designing the microthread implant model, microthreads were added to the implant neck in a computerized model. A force measuring 100 N was then applied to the entire surface of the abutment in the vertical direction. The results showed that in both models, stress was mainly concentrated at the cortical bone adjacent to the neck of the implant. Maximum stress values in the cortical bone...