Modelling Cell`s State in Different Cell Types, M.Sc. Thesis Sharif University of Technology ; Hossein Khalaj, Babak (Supervisor) ; Motahari, Abolfazl (Co-Supervisor)
Abstract
Existence of heterogeneity in vital tissues of complex multicellular organisms like mammals, and fatal tissues like cancer on one hand, and limited access to biological properties of their components on the other hand, turn the study of these tissue traits to one of the most interesting fields in bioinformatics. One of the hottest subjects in this field is the recognition of functional components of these tissues by using bulk data extracted from the whole tissue.Almost every method that aims to achieve such a purpose, particularly using gene expression data, assumes that all of the cell types which constitute the studied tissue have a deterministic expression profile.In this thesis we...
Cataloging briefModelling Cell`s State in Different Cell Types, M.Sc. Thesis Sharif University of Technology ; Hossein Khalaj, Babak (Supervisor) ; Motahari, Abolfazl (Co-Supervisor)
Abstract
Existence of heterogeneity in vital tissues of complex multicellular organisms like mammals, and fatal tissues like cancer on one hand, and limited access to biological properties of their components on the other hand, turn the study of these tissue traits to one of the most interesting fields in bioinformatics. One of the hottest subjects in this field is the recognition of functional components of these tissues by using bulk data extracted from the whole tissue.Almost every method that aims to achieve such a purpose, particularly using gene expression data, assumes that all of the cell types which constitute the studied tissue have a deterministic expression profile.In this thesis we...
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