Synthesis of N-Alkyl-1, 4 dihyroisoqinoline-3(2H)-one, M.Sc. Thesis Sharif University of Technology ; Matlubi Moghaddam, Firoz (Supervisor)
Abstract
Isoquinolinonese are important structural compounds in plant alkaloids and useful synthetic intermediates for bio logically active compound some 3(2H)-isoquinolinone are known to exhibit biological effects such as antidepressant, cardiotonic, or analgesic activity. 3(2H)-isoquinolinone and its derivative are not so readily accessible. They have previously been synthesized by the reaction of o-acylphenyl acetic with ammonia, reaction of 3-isochromanon with amines this methods have problems like low yield and because of that we have developed practical and efficient route to synthesis 1٬4 dihydroisoquin-3(2H)-ones under microwave irradiation. We did this project with modified Pictet-Spengler...
Cataloging briefSynthesis of N-Alkyl-1, 4 dihyroisoqinoline-3(2H)-one, M.Sc. Thesis Sharif University of Technology ; Matlubi Moghaddam, Firoz (Supervisor)
Abstract
Isoquinolinonese are important structural compounds in plant alkaloids and useful synthetic intermediates for bio logically active compound some 3(2H)-isoquinolinone are known to exhibit biological effects such as antidepressant, cardiotonic, or analgesic activity. 3(2H)-isoquinolinone and its derivative are not so readily accessible. They have previously been synthesized by the reaction of o-acylphenyl acetic with ammonia, reaction of 3-isochromanon with amines this methods have problems like low yield and because of that we have developed practical and efficient route to synthesis 1٬4 dihydroisoquin-3(2H)-ones under microwave irradiation. We did this project with modified Pictet-Spengler...
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