Alzheimer’s disease (AD) is a neurodegenerative disease which results in synaptic depression and complete destruction in neurons in the final stages. Many pathogenesis has so far been attributed to AD but the most commonly explained pathomechanism is based on the amyloid cascade theory which results in formation of amyloid beta plaques outside and hyper phosphorylated neurofibrillary tangles of tau protein inside the neurons. One of the most well-known symptoms of AD is the disability to learn and form new memories and transform them into long term memory. The most commonly studied mechanism in memory formation, is the “long term potentiation”. Although many mechanisms and molecules are...
Alzheimer’s disease (AD) is a neurodegenerative disease which results in synaptic depression and complete destruction in neurons in the final stages. Many pathogenesis has so far been attributed to AD but the most commonly explained pathomechanism is based on the amyloid cascade theory which results in formation of amyloid beta plaques outside and hyper phosphorylated neurofibrillary tangles of tau protein inside the neurons. One of the most well-known symptoms of AD is the disability to learn and form new memories and transform them into long term memory. The most commonly studied mechanism in memory formation, is the “long term potentiation”. Although many mechanisms and molecules are...