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    Graphene scaffolds in progressive nanotechnology/stem cell-based tissue engineering of the nervous system

    , Article Journal of Materials Chemistry B ; Volume 4, Issue 19 , 2016 , Pages 3169-3190 ; 20507518 (ISSN) Akhavan, O ; Sharif University of Technology
    Royal Society of Chemistry  2016
    Abstract
    Although graphene/stem cell-based tissue engineering has recently emerged and has promisingly and progressively been utilized for developing one of the most effective regenerative nanomedicines, it suffers from low differentiation efficiency, low hybridization after transplantation and lack of appropriate scaffolds required in implantations without any degrading in functionality of the cells. In fact, recent studies have demonstrated that the unique properties of graphene can successfully resolve all of these challenges. Among various stem cells, neural stem cells (NSCs) and their neural differentiation on graphene have attracted a lot of interest, because graphene-based neuronal tissue...