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Spectroscopic Study and Characterizing of Selenium Dioxide Complex with Pyridoxine(PN-Se):Interaction Between (PN-Se)and Bovine Serum Albumin
, M.Sc. Thesis Sharif University of Technology ; Mohamadi Boghaei, Davar (Supervisor)
Abstract
Temporary existence of some molecules like medicines in body and also existence of diagnostic agents in biological systems and study of the interactions of biomolecules with these agents is a matter of interest. It also may have an important role in design and synthesis of new drugs. Serum Albumin is the most abundant protein in circulation system in the body. So far, many studies about the interaction of this protein with different compounds have been undertaken. The aim of this paper was to synthesize selenium complex and analyze its potential biochemical activity in vitro. The concrete work falls into two parts:(1) to synthesize the selenium-pyridoxine compound (PNSe) (2) to probe into...
Investigation on the Ability of Pseudomonas Putida Bacterium for Biosorption of Se(IV) from the Aqueous Solutions
, M.Sc. Thesis Sharif University of Technology ; Outokesh, Mohammad (Supervisor) ; Keshtkar, Alireza (Supervisor) ; Sohbatzadeh, Hozhabr (Co-Supervisor)
Abstract
In this study, biosorption of selenium by Pseudomonas putida bacteria was investigated in both single and binary uptake systems. Bacteria cells were immobilized in the chitosan beads, to study impact of microorganism entrapment on the sorption capacity of the fabricated adsorbent. Uptake capacity increased by the entrapped bacterial weight percent up to 20 wt. %; but thereafter, sorption capacity gradually leveled off with an increase in the loading percentage of the bacterial cells.The effects of the three process variables including pH (2-6), biomass dosage (0.5-2.5 g/L) and initial concentration of selenium (50-250 mg/L) on the uptake performance of adsorbent were investigated, and...
Effects of bacillus amyloliquefaciens lfb112 on growth performance, carcass traits, immune, and serum biochemical response in broiler chickens
, Article Antibiotics ; Volume 10, Issue 11 , 2021 ; 20796382 (ISSN) ; Cheng, J ; Abbas, Z ; Cheng, Q ; Fan, Z ; Ahmad, B ; Hou, M ; Osman, G ; Guo, H ; Wang, J ; Zhang, R ; Sharif University of Technology
MDPI
2021
Abstract
This study aimed to investigate the effects of Bacillus amyloliquefaciens LFB112 on the growth performance, carcass traits, immune response, and serum biochemical parameters of broiler chickens. A total of 396 1 day old, mixed-sex commercial Ross 308 broilers with similar body weights were allotted into six treatment groups. The assigned groups were the CON group (basal diet with no supplement), AB (antibiotics) group (basal diet + 150 mg of aureomycin/kg), C+M group (basal diet + 5 × 108 CFU/kg B. amyloliquefaciens LFB112 powder with vegetative cells + metabolites), C group (basal diet + 5 × 108 CFU/kg B. amyloliquefaciens LFB112 vegetative cell powder with removed metabolites), M group...
Effects of bacillus amyloliquefaciens lfb112 on growth performance, carcass traits, immune, and serum biochemical response in broiler chickens
, Article Antibiotics ; Volume 10, Issue 11 , 2021 ; 20796382 (ISSN) ; Cheng, J ; Abbas, Z ; Cheng, Q ; Fan, Z ; Ahmad, B ; Hou, M ; Osman, G ; Guo, H ; Wang, J ; Zhang, R ; Sharif University of Technology
MDPI
2021
Abstract
This study aimed to investigate the effects of Bacillus amyloliquefaciens LFB112 on the growth performance, carcass traits, immune response, and serum biochemical parameters of broiler chickens. A total of 396 1 day old, mixed-sex commercial Ross 308 broilers with similar body weights were allotted into six treatment groups. The assigned groups were the CON group (basal diet with no supplement), AB (antibiotics) group (basal diet + 150 mg of aureomycin/kg), C+M group (basal diet + 5 × 108 CFU/kg B. amyloliquefaciens LFB112 powder with vegetative cells + metabolites), C group (basal diet + 5 × 108 CFU/kg B. amyloliquefaciens LFB112 vegetative cell powder with removed metabolites), M group...
Metabolomics analysis of the saliva in patients with chronic hepatitis b using nuclear magnetic resonance: A pilot study
, Article Iranian Journal of Basic Medical Sciences ; Volume 22, Issue 9 , 2019 , Pages 1044-1049 ; 20083866 (ISSN) ; Mohamadkhani, A ; Chashmniam, S ; Shahnazari, P ; Amini, M ; Arjmand, B ; Malekzadeh, R ; Nobakht Motlagh Ghoochani, B. F ; Sharif University of Technology
Mashhad University of Medical Sciences
2019
Abstract
Objective(s): Hepatitis B virus infection causes chronic disease such as cirrhosis and hepatocellular carcinoma. The metabolomics investigations have been demonstrated to be related to pathophysiologic mechanisms in many disorders such as hepatitis B infection. The aim of this study was to investigate the saliva metabolic profile of patients with chronic hepatitis B infection and to identify underlying mechanisms as well as potential biomarkers associated with the disease. Materials and Methods: Saliva from 16 healthy subjects and 20 patients with chronic hepatitis B virus were analyzed by nuclear magnetic resonance (NMR). Then, multivariate statistical analysis was performed to identify...
Graphene-based nanomaterials in fighting the most challenging viruses and immunogenic disorders
, Article ACS Biomaterials Science and Engineering ; Volume 8, Issue 1 , 2022 , Pages 54-81 ; 23739878 (ISSN) ; Asadi, M ; Akhavan, O ; Sharif University of Technology
American Chemical Society
2022
Abstract
Viral diseases have long been among the biggest challenges for healthcare systems around the world. The recent Coronavirus Disease 2019 (COVID-19) pandemic is an example of how complicated the situation can get if we are not prepared to combat a viral outbreak in time, which brings up the need for quick and affordable biosensing platforms and vast knowledge of potential antiviral effects and drug/gene delivery opportunities. The same challenges have also existed for nonviral immunogenic disorders. Nanomedicine is considered a novel candidate for effectively overcoming these worldwide challenges. Among the versatile nanomaterials commonly used in biomedical applications, graphene has recently...