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    Waste Water Purification of the Isfahan Zirconium Production Plant (ZPP) by Membrane Process

    , M.Sc. Thesis Sharif University of Technology Chaichi, Mahdieh (Author) ; Samad Fam, Mohammad (Supervisor) ; Yavari, Ramin (Supervisor) ; Haji Hosseini, Majid (Co-Supervisor)
    Abstract
    Isfahan Zirconium Production Plant (ZPP) is one of the most important plants in the nuclear industry of Islamic Republic of Iran. The wastewater of this plant contains high values of Sodium, Chloride, Nitrate and low values of Calcium, Magnesium, Zinc and Zirconium ions. Its release has been banned by international and national law because of the dangers and toxicity of its ions for the environment and living organisms. Therefore, its refinement as a compensation of Iran’s water resources in agriculture and drinking water has received a major consideration. Among the common methods to removal of these ions, membrane process method is selected due to it's major benefits such as not producing... 

    Exergy cost analysis of soil-plant system

    , Article International Journal of Exergy ; Volume 38, Issue 3 , 2022 , Pages 293-319 ; 17428297 (ISSN) Ledari, M. B ; Saboohi, Y ; Valero, A ; Azamian, S ; Sharif University of Technology
    Inderscience Publishers  2022
    Abstract
    In this paper, inspired by a gas turbine power plant, the interaction between plant-soil processes has been simulated. It is aimed to indicate that solar energy in the photosynthesis process is equivalent to the fuel in combustion chambers. In the glucose production process, when solar exergy is considered as a fuel, 99.4% of total exergy cost is supplied by solar exergy and only 0.6% of the exergy cost is provided by nutrients’ content. In general, 30% of the total exergy entering the Calvin cycle is consumed in glucose production and the remaining 70% is related to biomass generation (as flue gas in the gas turbine). Moreover, 98% of the total exergy cost of the soil box is related to... 

    Performances evaluation of Photo-Fenton process and Sonolysis for the treatment of Penicillin G formulation effluent

    , Article 1st 2011 International Conference on Environment Science and Biotechnology, ICESB 2011, Male, 25 November 2011 through 26 November 2011 ; Volume 8 , 2011 , Pages 202-208 ; 18780296 (ISSN) Saghafinia, M. S ; Emadian, S. M ; Vossoughi, M ; Sharif University of Technology
    Abstract
    Penicillin G is an active pharmaceutical ingredient of great importance in health sectors. Meanwhile, because of its huge quantity production and resistance to biodegradability, this antibiotic is ubiquitously presented in aquatic environment. In this study, the degradation of effluent wastewater from Penicillin G production plant by Photo- Fenton process and Ultrasound process (Sonolysis) was investigated, the effects of different process variables in both methods were evaluated and at last the degradation of Pen-G by these two processes in the optimum conditions was compared. Pen-G concentration and Chemical Oxygen Demand (COD) were selected as the environmental parameters to follow the... 

    Plant protein-based hydrophobic fine and ultrafine carrier particles in drug delivery systems

    , Article Critical Reviews in Biotechnology ; Volume 38, Issue 1 , 2018 , Pages 47-67 ; 07388551 (ISSN) Malekzad, H ; Mirshekari, H ; Sahandi Zangabad, P ; Moosavi Basri, S. M ; Baniasadi, F ; Sharifi Aghdam, M ; Karimi, M ; Hamblin, M. R ; Sharif University of Technology
    Taylor and Francis Ltd  2018
    Abstract
    For thousands of years, plants and their products have been used as the mainstay of medicinal therapy. In recent years, besides attempts to isolate the active ingredients of medicinal plants, other new applications of plant products, such as their use to prepare drug delivery vehicles, have been discovered. Nanobiotechnology is a branch of pharmacology that can provide new approaches for drug delivery by the preparation of biocompatible carrier nanoparticles (NPs). In this article, we review recent studies with four important plant proteins that have been used as carriers for targeted delivery of drugs and genes. Zein is a water-insoluble protein from maize; Gliadin is a 70% alcohol-soluble... 

    Substrate oscillations boost recombinant protein release from Escherichia coli

    , Article Bioprocess and Biosystems Engineering ; Volume 37, Issue 5 , May , 2014 , Pages 881-890 ; ISSN: 16157591 Jazini, M ; Herwig, C ; Sharif University of Technology
    Abstract
    Intracellular production of recombinant proteins in prokaryotes necessitates subsequent disruption of cells for protein recovery. Since the cell disruption and subsequent purification steps largely contribute to the total production cost, scalable tools for protein release into the extracellular space is of utmost importance. Although there are several ways for enhancing protein release, changing culture conditions is rather a simple and scalable approach compared to, for example, molecular cell design. This contribution aimed at quantitatively studying process technological means to boost protein release of a periplasmatic recombinant protein (alkaline phosphatase) from E. coli.... 

    Optimization of supercritical carbon dioxide extraction of essential oil from Dracocephalum kotschyi Boiss: An endangered medicinal plant in Iran

    , Article Journal of Chromatography A ; Volume 1422 , 2015 , Pages 73-81 ; 00219673 (ISSN) Nejad Sadeghi, M ; Taji, S ; Goodarznia, I ; Sharif University of Technology
    Elsevier  2015
    Abstract
    Extraction of the essential oil from a medicinal plant called Dracocephalum kotschyi Boiss was performed by green technology of supercritical carbon dioxide (SC-CO2) extraction. A Taguchi orthogonal array design with an OA16 (45) matrix was used to evaluate the effects of five extraction variables: pressure of 150-310bar, temperature of 40-60°C, average particle size of 250-1000μm, CO2 flow rate of 2-10ml/s and dynamic extraction time of 30-100min. The optimal conditions to obtain the maximum extraction yield were at 240bar, 60°C, 500μm, 10ml/s and 100min. The extraction yield under the above conditions was 2.72% (w/w) which is more than two times the maximum extraction yield that has been...