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    Variations in trunk muscle activities and spinal loads following posterior lumbar surgery: A combined in vivo and modeling investigation

    , Article Clinical Biomechanics ; Volume 30, Issue 10 , 2015 , Pages 1036-1042 ; 02680033 (ISSN) Jamshidnejad, S ; Arjmand, N ; Sharif University of Technology
    Abstract
    Background Iatrogenic injuries to paraspinal muscles during posterior lumbar surgery cause a reduction in their contractile cross-sectional area and thus presumably their postoperative activation. This study investigates the effect of such intraoperative injuries on postoperative patterns of muscle activations and spinal loads during various activities using a combined modeling and in vivo MR imaging approach. Methods A three-dimensional, multi-joint, musculoskeletal model was used to estimate pre- and postoperative muscle forces and spinal loads under various activities in upright and flexed postures. According to our in vivo pre- and postoperative (∼ 6 months) measurements in six patients... 

    Cross-sectional area of human trunk paraspinal muscles before and after posterior lumbar surgery using magnetic resonance imaging

    , Article European Spine Journal ; Volume 25, Issue 3 , 2016 , Pages 774-782 ; 09406719 (ISSN) Ghiasi, M. S ; Arjmand, N ; Shirazi Adl, A ; Farahmand, F ; Hashemi, H ; Bagheri, S ; Valizadeh, M ; Sharif University of Technology
    Springer Verlag 
    Abstract
    Atrogenic injuries to paraspinal muscles during the posterior lumbar surgery (PLS) cause a reduction in their cross-sectional areas (CSAs) and contractile densities over time post-surgery. This study aims to quantify such alterations. Method: Pre- and postoperative CSAs (~6 months interval) of all paraspinal muscles were measured in six patients undergoing PLS using a 3-T magnetic resonance (MR) scanner to quantify the alterations in geometrical and tissue effective contractile (non-fatty) CSAs of these muscles at all lumbar levels. To examine the presence of any confounding effects on recorded changes within ~7-month period, measurements were also carried out on ten healthy volunteers.... 

    Preoperative paraspinal neck muscle characteristics predict early onset adjacent segment degeneration in anterior cervical fusion patients: A machine-learning modeling analysis

    , Article Journal of Orthopaedic Research ; 2020 Wong, A. Y. L ; Harada, G ; Lee, R ; Gandhi, S. D ; Dziedzic, A ; Espinoza Orias, A ; Parnianpour, M ; Louie, P. K. H ; Basques, B ; An, H. S ; Samartzis, D ; Sharif University of Technology
    John Wiley and Sons Inc  2020
    Abstract
    Early onset adjacent segment degeneration (ASD) can be found within six months after anterior cervical discectomy and fusion (ACDF). Deficits in deep paraspinal neck muscles may be related to early onset ASD. This study aimed to determine whether the morphometry of preoperative deep neck muscles (multifidus and semispinalis cervicis) predicted early onset ASD in patients with ACDF. Thirty-two cases of early onset ASD after a two-level ACDF and 30 matched non-ASD cases were identified from a large-scale cohort. The preoperative total cross-sectional area (CSA) of bilateral deep neck muscles and the lean muscle CSAs from C3 to C7 levels were measured manually on T2-weighted magnetic resonance...