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    Magnetic carboxymethyl cellulose/silk fibroin hydrogel embedded with halloysite nanotubes as a biocompatible nanobiocomposite with hyperthermia application

    , Article Materials Chemistry and Physics ; Volume 287 , 2022 ; 02540584 (ISSN) Eivazzadeh Keihan, R ; Choopani, L ; Aghamirza Moghim Aliabadi, H ; Ganjali, F ; Kashtiaray, A ; Maleki, A ; Ahangari Cohan, R ; Salimi Bani, M ; Komijani, S ; Ahadian, M. M ; Salehpour, N ; Mahdavi, M ; Sharif University of Technology
    Elsevier Ltd  2022
    Abstract
    A novel and high potent magnetic nanobiocomposite was prepared based on Carboxymethyl cellulose (CMC) and epichlorohydrin (ECH) cross-linker interactions to form a three-dimensional cross-linked CMC hydrogel followed by silk fibroin (SF) and halloysite nanotubes (HNTs) modifications and further in situ Fe3O4 magnetic nanoparticles (MNPs) formation. Different analytical techniques like FT-IR, EDX, FE-SEM, XRD, TGA, and VSM were used to characterize the structure of the prepared nanobiocomposite. The spherical morphology of Fe3O4 MNPs and tubular HNTs were presented in the FE-SEM images. In biological tests, since the hemolysis percent was even less than the negative control, the CMC... 

    Hydroxyapatite based and anodic titania nanotube biocomposite coatings: fabrication, characterization and electrochemical behavior

    , Article Surface and Coatings Technology ; Volume 287 , 2016 , Pages 67-75 ; 02578972 (ISSN) Ahmadi, S ; Mohammadi, I ; Sadrnezhaad, S. K ; Sharif University of Technology
    Elsevier  2016
    Abstract
    The main challenges of biological implants are suitable strength, adhesion, biocompatibility and corrosion resistance. This paper discusses fabrication, characterization and electrochemical investigation of anodized Ti6Al4V without and with a hydroxyapatite (HA) layer, HA/TiO2 nanoparticles (NPs) and HA/TiO2 nanotubes (HA/anodized). X-ray diffraction (XRD), field emission scanning electron microscopy (FE-SEM) and energy dispersive spectroscopy (EDS) were used to characterize and compare properties of different samples. Dense HA with uniform distribution and 12.8 ± 2 MPa adhesive strength enhanced to 19.2 ± 4 MPa by the addition of TiO2 nanoparticles and enhanced to 23.1 ± 4 MPa by the... 

    Experimental investigation and finite element modelling of PMMA/carbon nanotube nanobiocomposites for bone cement applications

    , Article Soft Matter ; Volume 18, Issue 36 , 2022 , Pages 6800-6811 ; 1744683X (ISSN) Sadati, V ; Khakbiz, M ; Chagami, M ; Bagheri, R ; Chashmi, F. S ; Akbari, B ; Shakibania, S ; Lee, K. B ; Sharif University of Technology
    Royal Society of Chemistry  2022
    Abstract
    Multi-walled carbon nanotubes (MWCNTs) are one of the preferred candidates for reinforcing polymeric nanobiocomposites, such as acrylic bone type of cement. In this study, at first, bulk samples of the reinforced polymethylmethacrylate (PMMA) matrix were prepared with 0.1, 0.25, and 0.5 wt per wt% of MWCNTs by the casting method. Tensile and three-point bending tests were performed to determine the essential mechanical properties of bone cement, such as tensile and bending strengths. The tensile fracture surfaces were investigated by scanning electron microscopy (SEM). The commercial software (Abaqus) was used to conduct finite element analysis (FEA) by constructing a representative volume...