Sharif Digital Repository

In recent years, chromatographic techniques as one of the most important analytical techniques have been greatly developed from instrumentation and data volume point of views. On the other side, multivariate curve resolution (MCR) techniques as a branch of chemometrics have potential for the analysis of multivariate and huge data sets. In addition, MCR methods have been developed very fast in these years and their potential have been shown in the analysis of different types of chemical data. Thus, combination of sophisticated chromatographic techniques (e.g. gas chromatography-mass spectrometry (GC-MS) or comprehensive two-dimensional gas chromatography (GC×GC)) with MCR techniques can be... 

Fast, non-destructive and reliable methods for food authentication purposes have been deemed important in recent years. The hyperspectral imaging technique (HSI) is a powerful method in this field, allowing the study of different features such as size, color, texture. Comprehensive interpretation is crucial, and utilizing chemometric methods enhances data interpretation. Rice is a vital and strategic food source for nearly half of the world, with Asia, particularly Iran, being a leading producer and exporter. Various types of rice fraud exist, including the mixing of high-quality and low-quality varieties, sold at a high cost. The present project aims to determine the geographical origin and... 

With the expansion of the pharmaceutical market and the increasing likelihood of distributing substandard medicines, it is necessary to develop methods for rapid, timely, and non-destructive analysis. These methods should enable the assessment of qualitative features such as the amount of active substance and the homogeneous distribution of materials at various stages of drug manufacturing. In this regard, numerous studies have been conducted using spectroscopy and hyperspectral imaging, particularly in the visible and near-infrared regions. The challenge here is that active ingredients in medicine and excipients look very similar in this region. They're usually white powders, and the weak... 

These days, food authenticity has become a major challenge because food health directly affects human health. The importance of authenticity is highlighted when we are faced with foods with higher nutritional and economic value. Saffron is an important example of spices because in addition to having food coloring and flavoring properties, it also has numerous health benefits, but it has limited production and high price. Therefore, with the options available and cheaper to be replaced. Thus, among the various spices, cheating in saffron has the fourth place. Hyperspectral Imaging (HSI) has been developed for food safety industrial applications. This technique combines spectroscopy and... 

In recent years, comprehensive two-dimensional gas chromatography (GC×GC) has been widely used, especially in the separation and measurement of complex mixtures, due to its features such as higher peak capacity and better resolution in separation than usual chromatography methods, which the mixture analysis of polycyclic aromatic hydroarbons (PAHs) compounds have been targeted in this study. One of the main challenges in this field is the large amount of data and the qualitative and quantitative interpretation of the resulting data. Therefore, the identification, separation and quantitative measurement of species in this field is important, especially in the presence of interference in the...