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Utilizing a simulation approach for analysis of patient flow in the emergency department: a case study
, Article 15th Iran International Industrial Engineering Conference, IIIEC 2019, 23 January 2019 through 24 January 2019 ; 2019 , Pages 151-157 ; 9781728117751 (ISBN) ; Haji, B ; Shakhsi Niaei M ; Sharif University of Technology
Institute of Electrical and Electronics Engineers Inc
2019
Abstract
Simulation has been shown to be one of the most powerful tools in many areas of the health-care system, a system which attracted the attention of researchers due to its intricacy. The main goal of this study is to evaluate the patients' flow in an emergency department (ED). Discrete event simulation (DES)has been used as the core of this research so that it offers various ways to reduce the length of stay (LOS)of patients in different segments of ED by assessing various scenarios. In particular, a new approach for verification of the simulated model will be discussed. This study reports on the results that extracted from a case study on patient record data in one of the EDs located in Tehran...
A novel metabolic disorder in the degradation pathway of endogenous methanol due to a mutation in the gene of alcohol dehydrogenase
, Article Clinical Biochemistry ; Volume 90 , 2021 , Pages 66-72 ; 00099120 (ISSN) ; Nourbakhsh, M ; Vafadar, M ; Nourbakhsh, M ; Talebi, S ; Sharifi Zarchi, A ; Salehi Siavashani, E ; Garshasbi, M ; Sharif University of Technology
Elsevier Inc
2021
Abstract
Background: A small amount of methanol is produced endogenously in the human body but it is efficiently metabolized by alcohol dehydrogenase (ADH) and other enzymes, and the products eliminated without harm. In this study, we present a new entity of inborn error of methanol metabolism due to a mutation in the ADH1C gene coding for the γ subunit that is part of several ADH isoenzymes. Results: This disorder was discovered in an 11.58-year-old boy. During one 9-month hospital admission, he had periods of 1–4 days during which he was comatose, and between these periods he was sometimes verbose and euphoric, and had ataxia, dysarthria. Following hemodialysis treatments, he became conscious and...