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    Mathematical modeling of CSF pulsatile hydrodynamics based on fluid-solid interaction

    , Article IEEE Transactions on Biomedical Engineering ; Volume 57, Issue 6 , 2010 , Pages 1255-1263 ; 00189294 (ISSN) Masoumi, N ; Bastani, D ; Najarian, S ; Ganji, F ; Farmanzad, F ; Seddighi, A. S ; Sharif University of Technology
    2010
    Abstract
    Intracranial pressure (ICP) is derived from cerebral blood pressure and cerebrospinal fluid (CSF) circulatory dynamics and can be affected in the course of many diseases. Computer analysis of the ICP time pattern plays a crucial role in the diagnosis and treatment of those diseases. This study proposes the application of Linninger et al.s [IEEE Trans. Biomed. Eng. , vol. 52, no. 4, pp. 557565, Apr. 2005] fluidsolid interaction model of CSF hydrodynamic in ventricular system based on our clinical data from a group of patients with brain parenchyma tumor. The clinical experiments include the arterial blood pressure (ABP), venous blood pressure, and ICP in the subarachnoid space (SAS). These...