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Switching kalman filter based methods for apnea bradycardia detection from ECG signals
, Article Physiological Measurement ; Volume 36, Issue 9 , 2015 , Pages 1763-1783 ; 09673334 (ISSN) ; Shamsollahi, M. B ; Ge, D ; Hernandez, A. I ; Sharif University of Technology
Abstract
Apnea bradycardia (AB) is an outcome of apnea occurrence in preterm infants and is an observable phenomenon in cardiovascular signals. Early detection of apnea in infants under monitoring is a critical challenge for the early intervention of nurses. In this paper, we introduce two switching Kalman filter (SKF) based methods for AB detection using electrocardiogram (ECG) signal. The first SKF model uses McSharry's ECG dynamical model integrated in two Kalman filter (KF) models trained for normal and AB intervals. Whereas the second SKF model is established by using only the RR sequence extracted from ECG and two AR models to be fitted in normal and AB intervals. In both SKF approaches, a...
Mapping 123 million neonatal, infant and child deaths between 2000 and 2017
, Article Nature ; Volume 574, Issue 7778 , 2019 , Pages 353-358 ; 00280836 (ISSN) ; Henry, N. J ; Collison, M. L ; Marczak, L. B ; Sligar, A ; Watson, S ; Marquez, N ; Abbasalizad Farhangi, M ; Abbasi, M ; Abd-Allah, F ; Abdoli, A ; Abdollahi, M ; Abdollahpour, I ; Abdulkader, R. S ; Abrigo, M. R. M ; Acharya, D ; Adebayo, O. M ; Adekanmbi, V ; Adham, D ; Afshari, M ; Aghaali, M ; Ahmadi, K ; Ahmadi, M ; Ahmadpour, E ; Ahmed, R ; Akal, C. G ; Akinyemi, J. O ; Alahdab, F ; Alam, N ; Alamene, G. M ; Alene, K. A ; Alijanzadeh, M ; Alinia, C ; Alipour, V ; Aljunid, S. M ; Almalki, M. J ; Al-Mekhlafi, H. M ; Altirkawi, K ; Alvis-Guzman, N ; Amegah, A. K ; Amini, S ; Amit, A. M. L ; Anbari, Z ; Androudi, S ; Anjomshoa, M ; Ansari, F ; Antonio, C. A. T ; Arabloo, J ; Arefi, Z ; Aremu, O ; Armoon, B ; Arora, A ; Artaman, A ; Asadi, A ; Asadi Aliabadi, M ; Ashraf Ganjouei, A ; Assadi, R ; Ataeinia, B ; Atre, S. R ; Quintanilla, B. P. A ; Ayanore, M. A ; Azari, S ; Babaee, E ; Babazadeh, A ; Badawi, A ; Bagheri, S ; Bagherzadeh, M ; Baheiraei, N ; Balouchi, A ; Barac, A ; Bassat, Q ; Baune, B. T ; Bayati, M ; Bedi, N ; Beghi, E ; Behzadifar, M ; Behzadifar, M ; Belay, Y. B ; Bell, B ; Bell, M. L ; Berbada, D. A ; Bernstein, R. S ; Bhattacharjee, N. V ; Bhattarai, S ; Bhutta, Z. A ; Bijani, A ; Bohlouli, S ; Breitborde, N. J. K ; Britton, G ; Browne, A. J ; Nagaraja, S. B ; Busse, R ; Butt, Z. A ; Car, J ; Cárdenas, R ; Castañeda Orjuela, C. A ; Cerin, E ; Chanie, W. F ; Chatterjee, P ; Chu, D. T ; Cooper, C ; Costa, V. M ; Dalal, K ; Dandona, L ; Dandona, R ; Daoud, F ; Daryani, A ; Das Gupta, R ; Davis, I ; Davis Weaver, N ; Davitoiu, D. V ; De Neve, J. W ; Demeke, F. M ; Demoz, G. T ; Deribe, K ; Desai, R ; Deshpande, A ; Desyibelew, H. D ; Dey, S ; Dharmaratne, S. D ; Dhimal, M ; Diaz, D ; Doshmangir, L ; Duraes, A. R ; Dwyer Lindgren, L ; Earl, L ; Ebrahimi, R ; Ebrahimpour, S ; Effiong, A ; Eftekhari, A ; Ehsani Chimeh, E ; El Sayed, I ; El Sayed Zaki, M ; El Tantawi, M ; El-Khatib, Z ; Emamian, M. H ; Enany, S ; Eskandarieh, S ; Eyawo, O ; Ezalarab, M ; Faramarzi, M ; Fareed, M ; Faridnia, R ; Faro, A ; Fazaeli, A.A ; Fazlzadeh, M ; Fentahun, N ; Fereshtehnejad, S. M ; Fernandes, J. C ; Filip, I ; Fischer, F ; Foigt, N. A ; Foroutan, M ; Francis, J. M ; Fukumoto, T ; Fullman, N ; Gallus, S ; Gebre, D. G ; Gebrehiwot, T. T ; Gebremeskel, G. G ; Gessner, B. D ; Geta, B ; Gething, P. W ; Ghadimi, R ; Ghadiri, K ; Ghajarzadeh, M ; Ghashghaee, A ; Gill, P. S ; Gill, T. K ; Golding, N ; Gomes, N. G. M ; Gona, P. N ; Gopalani, S. V ; Gorini, G ; Goulart, B. N. G ; Graetz, N ; Greaves, F ; Green, M. S ; Guo, Y ; Haj-Mirzaian, A ; Haj-Mirzaian, A ; Hall, B. J ; Hamidi, S ; Haririan, H ; Haro, J. M ; Hasankhani, M ; Hasanpoor, E ; Hasanzadeh, A ; Hassankhani, H ; Hassen, H. Y ; Hegazy, M. I ; Hendrie, D ; Heydarpour, F ; Hird, T. R ; Hoang, C. L ; Hollerich, G ; Rad, E. H ; Hoseini Ghahfarokhi, M ; Hossain, N ; Hosseini, M ; Hosseinzadeh, M ; Hostiuc, M ; Hostiuc, S ; Househ, M ; Hsairi, M ; Ilesanmi, O. S ; Imani-Nasab, M. H ; Iqbal, U ; Irvani, S. S. N ; Islam, N ; Islam, S. M. S ; Jürisson, M ; Balalami, N. J ; Jalali, A ; Javidnia, J ; Jayatilleke, A. U ; Jenabi, E ; Ji, J. S ; Jobanputra, Y. B ; Johnson, K ; Jonas, J. B ; Shushtari, Z. J ; Jozwiak, J. J ; Kabir, A ; Kahsay, A ; Kalani, H ; Kalhor, R ; Karami, M ; Karki, S ; Kasaeian, A ; Kassebaum, N. J ; Keiyoro, P. N ; Kemp, G. R ; Khabiri, R ; Khader, Y. S ; Khafaie, M. A ; Khan, E. A ; Khan, J ; Khan, M. S ; Khang, Y. H ; Khatab, K ; Khater, A ; Khater, M. M ; Khatony, A ; Khazaei, M ; Khazaei, S ; Khazaei Pool, M ; Khubchandani, J ; Kianipour, N ; Kim, Y. J ; Kimokoti, R. W ; Kinyoki, D. K ; Kisa, A ; Kisa, S ; Kolola, T ; Kosen, S ; Koul, P. A ; Koyanagi, A ; Kraemer, M. U. G ; Krishan, K ; Krohn, K. J ; Kugbey, N ; Kumar, G. A ; Kumar, M ; Kumar, P ; Kuupiel, D ; Lacey, B ; Lad, S. D ; Lami, F. H ; Larsson, A. O ; Lee, P. H ; Leili, M ; Levine, A. J ; Li, S ; Lim, L. L ; Listl, S ; Longbottom, J ; Lopez, J. C. F ; Lorkowski, S ; Magdeldin, S ; Abd El Razek, H. M ; Abd El Razek, M. M ; Majeed, A ; Maleki, A ; Malekzadeh, R ; Malta, D. C ; Mamun, A. A ; Manafi, N ; Manda, A. L ; Mansourian, M ; Martins-Melo, F. R ; Masaka, A ; Massenburg, B. B ; Maulik, P. K ; Mayala, B. K ; Mazidi, M ; McKee, M ; Mehrotra, R ; Mehta, K. M ; Meles, G. G ; Mendoza, W ; Menezes, R. G ; Meretoja, A ; Meretoja, T. J ; Mestrovic, T ; Miller, T. R ; Miller-Petrie, M. K ; Mills, E. J ; Milne, G. J ; Mini, G. K ; Mir, S. M ; Mirjalali, H ; Mirrakhimov, E. M ; Mohamadi, E ; Mohammad, D. K ; Darwesh, A. M ; Mezerji, N. M. G ; Mohammed, A. S ; Mohammed, S ; Mokdad, A. H ; Molokhia, M ; Monasta, L ; Moodley, Y ; Moosazadeh, M ; Moradi, G ; Moradi, M ; Moradi, Y ; Moradi Lakeh, M ; Moradinazar, M ; Moraga, P ; Morawska, L ; Mosapour, A ; Mousavi, S. M ; Mueller, U. O ; Muluneh, A. G ; Mustafa, G ; Nabavizadeh, B ; Naderi, M ; Nagarajan, A. J ; Nahvijou, A ; Najafi, F ; Nangia, V ; Ndwandwe, D. E ; Neamati, N ; Negoi, I ; Negoi, R. I ; Ngunjiri, J. W ; Thi Nguyen, H. L ; Nguyen, L. H ; Nguyen, S. H ; Nielsen, K. R ; Ningrum, D. N. A ; Nirayo, Y. L ; Nixon, M. R ; Nnaji, C. A ; Nojomi, M ; Noroozi, M ; Nosratnejad, S ; Noubiap, J. J ; Motlagh, S. N ; Ofori Asenso, R ; Ogbo, F. A ; Oladimeji, K. E ; Olagunju, A. T ; Olfatifar, M ; Olum, S ; Olusanya, B. O ; Oluwasanu, M. M ; Onwujekwe, O. E ; Oren, E ; Ortega Altamirano, D. D. V ; Ortiz, A ; Osarenotor, O ; Osei, F. B ; Osgood-Zimmerman, A. E ; Otstavnov, S. S ; Owolabi, M. O ; Mahesh, P. A ; Pagheh, A.S ; Pakhale, S ; Panda Jonas, S ; Pandey, A ; Park, E. K ; Parsian, H ; Pashaei, T ; Patel, S. K ; Pepito, V. C. F ; Pereira, A ; Perkins, S ; Pickering, B. V ; Pilgrim, T ; Pirestani, M ; Piroozi, B ; Pirsaheb, M ; Plana Ripoll, O ; Pourjafar, H ; Puri, P ; Qorbani, M ; Quintana, H ; Rabiee, M ; Sharif University of Technology
Nature Publishing Group
2019
Abstract
Since 2000, many countries have achieved considerable success in improving child survival, but localized progress remains unclear. To inform efforts towards United Nations Sustainable Development Goal 3.2—to end preventable child deaths by 2030—we need consistently estimated data at the subnational level regarding child mortality rates and trends. Here we quantified, for the period 2000–2017, the subnational variation in mortality rates and number of deaths of neonates, infants and children under 5 years of age within 99 low- and middle-income countries using a geostatistical survival model. We estimated that 32% of children under 5 in these countries lived in districts that had attained...
Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950–2019: a comprehensive demographic analysis for the Global Burden of Disease Study 2019
, Article The Lancet ; Volume 396, Issue 10258 , 2020 , Pages 1160-1203 ; Machado, D.B ; Cislaghi, B ; Salman, O.M ; Karanikolos, M ; McKee, M ; Abbas, K.M ; Brady, O.J ; Larson, H.J ; Trias-Llimós, S ; Cummins, S ; Langan, S.M ; Sartorius, B ; Hafiz, A ; Jenabi, E ; Mohammad Gholi Mezerji, N ; Borzouei, S ; Azarian, G ; Khazaei, S ; Abbasi, M ; Asghari, B ; Masoumi, S ; Komaki, H ; Taherkhani, A ; Adabi, M ; Abbasifard, M ; Bazmandegan, G ; Kamiab, Z ; Vakilian, A ; Anjomshoa, M ; Mokari, A ; Sabour, S ; Shahbaz, M ; Saeedi, R ; Ahmadieh, H ; Yousefinezhadi, T ; Haj-Mirzaian, A ; Nikbakhsh, R ; Safi, S ; Asgari, S ; Irvani, S.N ; Jahanmehr, N ; Ramezanzadeh, K ; Abbasi-Kangevari, M ; Khayamzadeh, M ; Abbastabar, H ; Shirkoohi, R ; Fazlzadeh, M ; Janjani, H ; Hosseini, M ; Mansournia, M ; Tohidinik, H ; Bakhtiari, A ; Fazaeli, A ; Mousavi, S ; Hasanzadeh, A ; Nabavizadeh, B ; Malekzadeh, R ; Hashemian, M ; Pourshams, A ; Salimzadeh, H ; Sepanlou, S.G ; Afarideh, M ; Esteghamati, A ; Esteghamati, S ; Ghajar, A ; Heidari, B ; Rezaei, N ; Mohamadi, E ; Rahimi-Movaghar, A ; Rahim, F ; Eskandarieh, S ; Sahraian, M ; Mohebi, F ; Aminorroaya, A ; Ebrahimi, H ; Farzadfar, F ; Mohajer, B ; Pishgar, F ; Saeedi Moghaddam, S ; Shabani, M ; Zarafshan, H ; Abolhassani, H ; Hafezi-Nejad, N ; Heidari-Soureshjani, R ; Abdollahi, M ; Farahmand, M ; Salamati, P ; Mehrabi Nasab, E ; Tajdini, M ; Aghamir, S ; Mirzaei, R ; Dibaji Forooshani, Z ; Khater, M.M ; Abd-Allah, F ; Abdelalim, A ; Abualhasan, A ; El-Jaafary, S.I ; Hassan, A ; Elsharkawy, A ; Khater, A.M ; Elhabashy, H.R ; Salem, M.R.R ; Salem, H ; Sadeghi, M ; Jafarinia, M ; Amini-Rarani, M ; Mohammadifard, N ; Sarrafzadegan, N ; Abdollahpour, I ; Sarveazad, A ; Tehrani-Banihashemi, A ; Yoosefi Lebni, J ; Manafi, N ; Pazoki Toroudi, H ; Dorostkar, F ; Alipour, V ; Sheikhtaheri, A ; Arabloo, J ; Azari, S ; Ghashghaee, A ; Rezapour, A ; Naserbakht, M ; Kabir, A ; Mehri, F ; Yousefifard, M ; Asadi-Aliabadi, M ; Babaee, E ; Eshrati, B ; Goharinezhad, S ; Moradi-Lakeh, M ; Abedi, P ; Rashedi, V ; Kumar, V ; Elgendy, I.Y ; Basu, S ; Park, J ; Pereira, A ; Norheim, O.F ; Eagan, A.W ; Cahill, L.E ; Sheikh, A ; Abushouk, A.I ; Kraemer, M.U.G ; Thakur, B ; Bärnighausen, T.W ; Shrime, M.G ; Abedi, A ; Doshi, C.P ; Abegaz, K.H ; Geberemariyam, B.S ; Aynalem, Y.A ; Shiferaw, W.S ; Abosetugn, A.E ; Aboyans, V ; Abrams, E.M ; Gitimoghaddam, M ; Kissoon, N ; Stubbs, J.L ; Brauer, M ; Iyamu, I.O ; Kopec, J.A ; Pourmalek, F ; Ribeiro, A.P ; Malta, D.C ; Gomez, R.S ; Abreu, L.G ; Abrigo, M.R.M ; Almulhim, A.M ; Dahlawi, S.M.A ; Pottoo, F.H ; Menezes, R.G ; Alanzi, T.M ; Alumran, A.K ; Abu Haimed, A.K ; Madadin, M ; Alanezi, F.M ; Abu-Gharbieh, E ; Saddik, B ; Abu-Raddad, L.J ; Samy, A.M ; El Nahas, N ; Shalash, A.S ; Nabhan, A.F ; Kamath, A.M ; Kassebaum, N.J ; Aravkin, A.Y ; Kochhar, S ; Sorensen, R.J.D ; Afshin, A ; Burkart, K ; Cromwell, E.A ; Dandona, L ; Dharmaratne, S.D ; Gakidou, E ; Hay, S.I ; Kyu, H.H ; Lopez, A.D ; Lozano, R ; Misganaw, A.T ; Mokdad, A.H ; Naghavi, M ; Pigott, D.M ; Reiner Jr, R.C ; Roth, G.A ; Stanaway, J.D ; Vollset, S ; Vos, T ; Wang, H ; Lim, S.S ; Murray, C.J.L ; Kalani, R ; Ikuta, K.S ; Cho, D.Y ; Kneib, C.J ; Crowe, C.S ; Massenburg, B.B ; Morrison, S.D ; Acebedo, A ; Adelson, J.D ; Agesa, K.M ; Alam, T ; Albertson, S.B ; Anderson, J.A ; Antony, C.M ; Ashbaugh, C ; Assmus, M ; Azhar, G ; Balassyano, S ; Bannick, M.S ; Barthelemy, C.M ; Bender, R.G ; Bennitt, F.B ; Bertolacci, G.J ; Biehl, M.H ; Bisignano, C ; Boon-Dooley, A.S ; Briant, P.S ; Bryazka, D ; Bumgarner, B.R ; Callender, C.S ; Cao, J ; Castle, C.D ; Castro, E ; Causey, K ; Cercy, K.M ; Chalek, J ; Charlson, F.J ; Cohen, A.J ; Comfort, H ; Compton, K ; Croneberger, A.J ; Cruz, J.A ; Cunningham, M ; Dandona, R ; Dangel, W.J ; Dean, F.E ; DeCleene, N.K ; Deen, A ; Degenhardt, L ; Dingels, Z.V ; Dippenaar, I.N ; Dirac, M.A ; Dolgert, A.J ; Emmons-Bell, S ; Estep, K ; Farag, T ; Feigin, V.L ; Feldman, R ; Ferrara, G ; Ferrari, A.J ; Fitzgerald, R ; Force, L.M ; Fox, J.T ; Frank, T.D ; Fu, W ; Fukutaki, K ; Fuller, J.E ; Fullman, N ; Galles, N.C ; Gardner, W.M ; Gershberg Hayoon, A ; Goren, E ; Gorman, T.M ; Gottlich, H.C ; Guo, G ; Haddock, B ; Hagins, H ; Haile, L.M ; Hamilton, E.B ; Han, C ; Han, H ; Harvey, J.D ; Henny, K ; Henrikson, H.J ; Henry, N.J ; Herbert, M.E ; Hsiao, T ; Huynh, C.K ; Iannucci, V.C ; Ippolito, H ; Irvine, C.M.S ; Jafari, H ; Jahagirdar, D ; James, S.L ; Johnson, C.O ; Johnson, S.C ; Keller, C ; Kemmer, L ; Kendrick, P.J ; Knight, M ; Kocarnik, J.M ; Krohn, K.J ; Larson, S.L ; Lau, K.M ; Ledesma, J.R ; Leever, A.T ; LeGrand, K.E ; Lescinsky, H ; Lin, C ; Liu, H ; Liu, Z ; Lo, J ; Lu, A ; Ma, J ; Maddison, E.R ; Manguerra, H ; Marks, A ; Martopullo, I ; Mastrogiacomo, C.I ; May, E.A ; Mooney, M.D ; Mosser, J.F ; Mullany, E.C ; Mumford, J ; Munro, S.B ; Nandakumar, V ; Nguyen, J ; Nguyen, M ; Nichols, E ; Nixon, M.R ; Odell, C.M ; Ong, K.L ; Orji, A.U ; Ostroff, S.M ; Pasovic, M ; Paulson, K.R ; Pease, S.A ; Pennini, A ; Pierce, M ; Pilz, T.M ; Pletcher, M ; Rao, P.C ; Razo, C ; Redford, S.B ; Reinig, N ; Reitsma, M.B ; Rhinehart, P ; Robalik, T ; Roberts, S ; Roberts, N.L.S ; Rolfe, S ; Sbarra, A.N ; Schaeffer, L.E ; Shackelford, K.A ; Shadid, J ; Sharara, F ; Shaw, D.H ; Sheena, B.S ; Simpson, K.E ; Smith, A ; Spencer, C.N ; Spurlock, E.E ; Stark, B.A ; Steiner, C ; Steuben, K.M ; Sylte, D.O ; Tang, M ; Taylor, H.J ; Terrason, S ; Thomson, A.M ; Torre, A.E ; Travillian, R ; Troeger, C.E ; Vongpradith, A ; Walters, M.K ; Wang, J ; Watson, A ; Watson, S ; Whisnant, J.L ; Whiteford, H.A ; Wiens, K.E ; Wilner, L.B ; Wilson, S ; Wool, E.E ; Wozniak, S.S ; Wu, J ; Wulf Hanson, S ; Wunrow, H ; Xu, R ; Sharif University of Technology
Lancet Publishing Group
2020
Abstract
Background: Accurate and up-to-date assessment of demographic metrics is crucial for understanding a wide range of social, economic, and public health issues that affect populations worldwide. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 produced updated and comprehensive demographic assessments of the key indicators of fertility, mortality, migration, and population for 204 countries and territories and selected subnational locations from 1950 to 2019. Methods: 8078 country-years of vital registration and sample registration data, 938 surveys, 349 censuses, and 238 other sources were identified and used to estimate age-specific fertility. Spatiotemporal...
, M.Sc. Thesis Sharif University of Technology ; Shamsollahi, Mohammad Bagher (Supervisor)
Abstract
Apnea-bradycardia is a medical term for prolonged respiratory pause accompanied with a heart rate reduction which is a common event among preterm infants. Repetition of apnea-bradycardia episodescompromises oxygenation and tissue perfusion and may lead to neurological impairment or even short-term morbi-mortality. Main solution to this breathing-related disorder is continues monitoring of infants in neonatal intensive care units in order to detect apnea-bradycardia event, generate an alarm and warn available nurse or physician to initiate quick nursing actions. Various studies have been done in this area and different methods are proposed which mainly focus on cardiac signal processing. This...
Evaluating the Consequences of Salamat Universal Insurance on Healthcare Utilization and Infant Mortality
, M.Sc. Thesis Sharif University of Technology ; Fatemi, Farshad (Supervisor) ; Vesal, Mohammad (Supervisor)
Abstract
In 2014, Iranian government initiated “Salamat” universal insurance program, aiming to provide free health insurance coverage for the uninsured population. Consequently, more than 10 million individuals enrolled in the program, and insurance coverage rose 15 percentage points among the urban population. The purpose of this study is to evaluate the program’s consequences on healthcare utilization and mortality of various age-groups. To this end, we have estimated data on healthcare utilization from the results of “Households Expenditures and Income Survey” for years 2011-2017, and also used the data on the frequency of mortality of each age-group taken from the National Organization for Civil...
Early detection of apnea-bradycardia episodes in preterm infants based on coupled hidden Markov model
, Article IEEE International Symposium on Signal Processing and Information Technology, IEEE ISSPIT 2013 ; 2013 , Pages 243-248 ; Montazeri, N ; Shamsollahi, M. B ; Ge, D ; Beuchee, A ; Pladys, P ; Hernandez, A. I ; Sharif University of Technology
IEEE Computer Society
2013
Abstract
The incidence of apnea-bradycardia episodes in preterm infants may lead to neurological disorders. Prediction and detection of these episodes are an important task in healthcare systems. In this paper, a coupled hidden Markov model (CHMM) based method is applied to detect apnea-bradycardia episodes. This model is evaluated and compared with two other methods based on hidden Markov model (HMM) and hidden semi-Markov model (HSMM). Evaluation and comparison are performed on a dataset of 233 apnea-bradycardia episodes which have been manually annotated. Observations are composed of RR-interval time series and QRS duration time series. The performance of each method was evaluated in terms of...
Detection of Apnea Bradycardia from ECG Signals of Preterm Infants Using Layered Hidden Markov Model
, Article Annals of Biomedical Engineering ; Volume 49, Issue 9 , 2021 , Pages 2159-2169 ; 00906964 (ISSN) ; Shamsollahi, M. B ; Fatemizadeh, E ; Beuchée, A ; Hernández, A. I ; Montazeri Ghahjaverestan, N ; Sharif University of Technology
Springer
2021
Abstract
Apnea-bradycardia (AB) is a common complication in prematurely born infants, which is associated with reduced survival and neurodevelopmental outcomes. Thus, early detection or predication of AB episodes is critical for initiating preventive interventions. To develop automatic real-time operating systems for early detection of AB, recent advances in signal processing can be employed. Hidden Markov Models (HMM) are probabilistic models with the ability of learning different dynamics of the real time-series such as clinical recordings. In this study, a hierarchy of HMMs named as layered HMM was presented to detect AB episodes from pre-processed single-channel Electrocardiography (ECG). For...
Wolfram-like syndrome with bicuspid aortic valve due to a homozygous missense variant in CDK13
, Article Journal of Human Genetics ; Volume 66, Issue 10 , 2021 , Pages 1009-1018 ; 14345161 (ISSN) ; Raza, S. I ; Anwar, M. Z ; Bharadwaj, T ; Liaqat, K ; Khokhar, M. A. S ; Everard, J. L ; Nasir, A ; Nickerson, D. A ; Bamshad, M. J ; Ansar, M ; Schrauwen, I ; Ahmad, W ; Leal, S. M ; University of Washington Center for Mendelian Genomics ; Sharif University of Technology
Springer Nature
2021
Abstract
Background: Wolfram syndrome (WFS) is characterized by deafness, diabetes mellitus, and diabetes insipidus along with optic atrophy. WFS has an autosomal recessive mode of inheritance and is due to variants in WFS1 and CISD2. Methods: We evaluated the underlying molecular etiology of three affected members of a consanguineous family with hearing impairment, bicuspid aortic valve, diabetes mellitus and insipidus, clinodactyly, and gastrointestinal tract abnormalities via exome sequencing approach. We correlated clinical and imaging data with the genetic findings and their associated phenotypes. Results: We identified a homozygous missense variant p.(Asn1097Lys) in CDK13, a gene previously...
Mapping geographical inequalities in oral rehydration therapy coverage in low-income and middle-income countries, 2000-17
, Article The Lancet Global Health ; Volume 8, Issue 8 , 2020 , Pages e1038-e1060 ; Lindstedt, P. A ; Blacker, B. F ; Johnson, K. B ; Baumann, M. M ; Schaeffer, L. E ; Abbastabar, H ; Abd Allah, F ; Abdelalim, A ; Abdollahpour, I ; Abegaz, K. H ; Abejie, A. N ; Abreu, L. G ; Abrigo, M. R. M ; Abualhasan, A ; Accrombessi, M. M. K ; Acharya, D ; Adabi, M ; Adamu, A. A ; Adebayo, O. M ; Adedoyin, R. A ; Adekanmbi, V ; Adetokunboh, O. O ; Adhena, B. M ; Afarideh, M ; Ahmad, S ; Ahmadi, K ; Ahmed, A. E ; Ahmed, M. B ; Ahmed, R ; Akalu, T. Y ; Alahdab, F ; A Aly, Z ; Alam, N ; Alam, S ; Alamene, G. M ; Alanzi, T. M ; Alcalde Rabanal, J. E ; Ali, B. A ; Alijanzadeh, M ; Alipour, V ; Aljunid, S. M ; Almasi, A ; Almasi Hashiani, A ; Al Mekhlafi, H. M ; Altirkawi, K. A ; Alvis Guzman, N ; Alvis Zakzuk, N. J ; Amini, S ; Amit, A. M. L ; Andrei, C. L ; Anjomshoa, M ; Anoushiravani, A ; Ansari, F ; Antonio, C. A. T ; Antony, B ; Antriyandarti, E ; Arabloo, J ; Aref, H. M. A ; Aremu, O ; Armoon, B ; Arora, A ; Aryal, K. K ; Arzani, A ; Asadi Aliabadi, M ; Atalay, H. T ; Athari, S. S ; Athari, S. M ; Atre, S. R ; Ausloos, M ; Awoke, N ; Ayala Quintanilla, B. P ; Ayano, G ; Ayanore, M. A ; Aynalem, Y. A ; Azari, S ; Azzopardi, P. S ; Babaee, E ; Babalola, T. K ; Badawi, A ; Bairwa, M ; Bakkannavar, S. M ; Balakrishnan, S ; Bali, A. G ; Banach, M ; Banoub, J. A. M ; Barac, A ; Bärnighausen, T. W ; Basaleem, H ; Basu, S ; Bay, V. D ; Bayati, M ; Baye, E ; Bedi, N ; Beheshti, M ; Behzadifar, M ; Behzadifar, M ; Bekele, B. B ; Belayneh, Y. M ; Bell, M. L ; Bennett, D. A ; Berbada, D. A ; Bernstein, R. S ; Bhat, A. G ; Bhattacharyya, K ; Bhattarai, S ; Bhaumik, S ; Bhutta, Z. A ; Bijani, A ; Bikbov, B ; Birihane, B. M ; Biswas, R. K ; Bohlouli, S ; Bojia, H. A ; Boufous, S ; Brady, O. J ; Bragazzi, N. L ; Briko, A. N ; Briko, N. I ; Britton, G. B ; Burugina Nagaraja, S ; Busse, R ; Butt, Z. A ; Cámera, L. A ; Campos Nonato, I. R ; Cano, J ; Car, J ; Cárdenas, R ; Carvalho, F ; Castañeda Orjuela, C. A ; Castro, F ; Chanie, W. F ; Chatterjee, P ; Chattu, V. K ; Chichiabellu, T. Y ; Chin, K. L ; Christopher, D. J ; Chu, D. T ; Cormier, N. M ; Costa, V. M ; Culquichicon, C ; Daba, M. S ; Damiani, G ; Dandona, L ; Dandona, R ; Dang, A. K ; Darwesh, A. M ; Darwish, A. H ; Daryani, A ; Das, J. K ; Das Gupta, R. D ; Dash, A. P ; Davey, G ; Dávila Cervantes, C. A ; Davis, A. C ; Davitoiu, D. V ; De la Hoz, F. P ; Demis, A. B ; Demissie, D. B ; Demissie, G. D ; Demoz, G. T ; Denova Gutiérrez, E ; Deribe, K ; Desalew, A ; Deshpande, A ; Dharmaratne, S. D ; Dhillon, P ; Dhimal, M ; Dhungana, G. P ; Diaz, D ; Dipeolu, I. O ; Djalalinia, S ; Doyle, K. E ; Dubljanin, E ; Duko, B ; Duraes, A. R ; Ebrahimi Kalan, M ; Edinur, H. A ; Effiong, A ; Eftekhari, A ; El Nahas, N ; El Sayed, I ; El Sayed Zaki, M ; El Tantawi, M ; Elema, T. B ; Elhabashy, H. R ; El-Jaafary, S. I ; Elkout, H ; Elsharkawy, A ; Elyazar, I. R. F ; Endalamaw, A ; Endalew, D. A ; Eskandarieh, S ; Esteghamati, A ; Esteghamati, S ; Etemadi, A ; Ezekannagha, O ; Fareed, M ; Faridnia, R ; Farzadfar, F ; Fazlzadeh, M ; Feigin, V. L ; Fereshtehnejad, S. M ; Fernandes, E ; Filip, I ; Fischer, F ; Foigt, N. A ; Folayan, M. O ; Foroutan, M ; Franklin, R. C ; Fukumoto, T ; Gad, M. M ; Gayesa, R. T ; Gebre, T ; Gebremedhin, K. B ; Gebremeskel, G. G ; Gesesew, H. A ; Gezae, K. E ; Ghadiri, K ; Ghashghaee, A ; Ghimire, P. R ; Gill, P. S ; Gill, T. K ; Ginindza, T. G ; Gomes, N. G ; Gopalani, S. V ; Goulart, A. C ; Goulart, B. N. G ; Grada, A ; Gubari, M. I. M ; Gugnani, H. C ; Guido, D ; Guimarães, R. A ; Guo, Y ; Gupta, R ; Hafezi Nejad, N ; Haile, D. H ; Hailu, G. B ; Haj Mirzaian, A ; Haj Mirzaian, A ; Hamadeh, R. R ; Hamidi, S ; Handiso, D. W ; Haririan, H ; Hariyani, N ; Hasaballah, A. I ; Hasan, M. M ; Hasanpoor, E ; Hasanzadeh, A ; Hassankhani, H ; Hassen, H. Y ; Hegazy, M. I ; Heibati, B ; Heidari, B ; Hendrie, D ; Henry, N. 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M ; Khayamzadeh, M ; Khazaei, M ; Khazaei, S ; Khosravi, M. H ; Khubchandani, J ; Kiadaliri, A ; Kim, Y. J ; Kimokoti, R. W ; Kisa, A ; Kisa, S ; Kissoon, N ; Shivakumar, K. M ; Kochhar, S ; Kolola, T ; Komaki, H ; Kosen, S ; Koul, P. A ; Koyanagi, A ; Kraemer, M. U. G ; Krishan, K ; Kugbey, N ; Kumar, G. A ; Kumar, M ; Kumar, P ; Kumar, V ; Kusuma, D ; La Vecchia, C ; Lacey, B ; Lad, S. D ; Lal, D. K ; Lam, F ; Lami, F. H ; Lamichhane, P ; Lansingh, V. C ; Lasrado, S ; Laxmaiah, A ; Lee, P. H ; LeGrand, K. E ; Leili, M ; Lenjebo, T. L ; Leshargie, C. T ; Levine, A. J ; Li, S ; Linn, S ; Liu, S ; Liu, S ; Lodha, R ; Longbottom, J ; Lopez, J. C. F ; Magdy Abd El Razek, H ; Magdy Abd El Razek, M ; Mahadeshwara Prasad, DR ; Mahasha, P. W ; Mahotra, N. B ; Majeed, A ; Malekzadeh, R ; Malta, D. C ; Mamun, A. A ; Manafi, N ; Manda, A. L ; Manohar, N. D. D ; Mansournia, M. A ; Mapoma, C. C ; Maravilla, J. C ; Martinez, G ; Martini, S ; Martins-Melo, F. R ; Masaka, A ; Massenburg, B. B ; Mathur, M. R ; Mayala, B. K ; Mazidi, M ; McAlinden, C ; Meharie, B. G ; Mehndiratta, M. M ; Mehta, K. M ; Sharif University of Technology
Elsevier Ltd
2020
Abstract
Background: Oral rehydration solution (ORS) is a form of oral rehydration therapy (ORT) for diarrhoea that has the potential to drastically reduce child mortality; yet, according to UNICEF estimates, less than half of children younger than 5 years with diarrhoea in low-income and middle-income countries (LMICs) received ORS in 2016. A variety of recommended home fluids (RHF) exist as alternative forms of ORT; however, it is unclear whether RHF prevent child mortality. Previous studies have shown considerable variation between countries in ORS and RHF use, but subnational variation is unknown. This study aims to produce high-resolution geospatial estimates of relative and absolute coverage of...
The global burden of childhood and adolescent cancer in 2017: an analysis of the Global Burden of Disease Study 2017
, Article The Lancet Oncology ; Volume 20, Issue 9 , 2019 , Pages 1211-1225 ; 14702045 (ISSN) ; Abdollahpour, I ; Advani, S.M ; Agius, D ; Ahmadian, E ; Alahdab, F ; Alam, T ; Alebel, A ; Alipour, V ; Allen, C.A ; Almasi Hashiani, A ; Alvarez, E.M ; Amini, S ; Amoako, Y.A ; Anber, N.H ; Arabloo, J ; Artaman, A ; Atique, S ; Awasthi, A ; Bagherzadeh, M ; Basaleem, H ; Bekru, E.T ; Bijani, A ; Bogale, K.A ; Car, M ; Carvalho, F ; Castro, C ; Catalá-López, F ; Chu, D.-T ; Costa, V.M ; Darwish, A.H ; Demeke, F.M ; Demis, A.B ; Demoz, G.T ; Dharmaratne, S.D ; Do, H.P ; Doan, L.P ; Dubey, M ; Eftekhari, A ; El-Khatib, Z ; Emamian, M.H ; Abbasalizad Farhangi, M ; Fernandes, E ; Fischer, F ; Fouladi Fard, R ; Friedrich, P.M ; Fukumoto, T ; Gedefaw, G.A ; Ghashghaee, A ; Gholamian, A ; Haj-Mirzaian, A ; Haj-Mirzaian, A ; Hamidi, S ; Harvey, J.D ; Hassen, H.Y ; Hay, S.I ; Hoang, C.L ; Hole, M.K ; Horita, N ; Hosseini, S.N ; Hosseinzadeh, M ; Hsairi, M ; Hudson, M.M ; Innos, K ; Jalilian, F ; James, S.L ; Kasaeian, A ; Kassa, T.D ; Kassebaum, N.J ; Keiyoro, P.N ; Khader, Y.S ; Khubchandani, J ; Kianipour, N ; Kirby, J ; Kisa, A ; Kisa, S ; Kocarnik, J.M ; Lauriola, P ; Lopez, A.D ; Mägi, M ; Malik, M.A ; Manafi, A ; Manafi, N ; Mansournia, M.A ; Massenburg, B.B ; Mehta, V ; Meles, H.G ; Meretoja, T.J ; Mestrovic, T ; Mirzaei Alavijeh, M ; Mir, S.M ; Mohammad, D.K ; Darwesh, A.M ; Mezerji, N.M.G ; Mohammadibakhsh, R ; Mohammadoo Khorasani, M ; Mokdad, A.H ; Moodley, Y ; Moosazadeh, M ; Moossavi, M ; Moradpour, F ; Morrison, S.D ; Muchie, K.F ; Naghavi, M ; Nazari, J ; Ngunjiri, J.W ; Nguyen, C.T ; Nguyen, L.H ; Nguyen, S.H ; Nguyen, T.H ; Nixon, M.R ; Olagunju, A.T ; Olagunju, T.O ; Ong, S.K ; Paapsi, K ; Pennini, A ; Pereira, D.M ; Pillay, J.D ; Qorbani, M ; Rabiee, M ; Rabiee, N ; Raoofi, S ; Rawaf, D.L ; Rawaf, S ; Reiner, R.C ; Rezaei, N ; Rezapour, A ; Roba, K.T ; Robison, L.L ; Rodriguez Galindo, C ; Roshandel, G ; Safiri, S ; Salahshoor, M ; Salehi Zahabi, S ; Samy, A.M ; Santric Milicevic, M.M ; Satpathy, M ; Sawyer, S.M ; Seyedmousavi, S ; Shabaninejad, H ; Shaikh, M.A ; Shamshirian, A ; Shamsizadeh, M ; Shirkoohi, R ; Siabani, S ; Singh, J.A ; Siramlee, K ; Tabarés-Seisdedos, R ; Temsah, M.-H ; Tran, B.X ; Ullah, I ; Vahedian Azimi, A ; Vollset, S.E ; Vos, T ; Waheed, Y ; Weldesamuel, G.T ; Workie, H.M ; Xu, R ; Yaseri, M ; Yonemoto, N ; Yu, C ; Zadnik, V ; Zahirian Moghadam, T ; Zaidi, Z ; Zangeneh, A ; Zewale, T.A ; Ziapour, A ; Zodpey, S ; Murray, C.J.L ; Fitzmaurice, C ; Bhakta, N ; GBD 2017 Childhood Cancer Collaborators ; Sharif University of Technology
Lancet Publishing Group
2019
Abstract
Background: Accurate childhood cancer burden data are crucial for resource planning and health policy prioritisation. Model-based estimates are necessary because cancer surveillance data are scarce or non-existent in many countries. Although global incidence and mortality estimates are available, there are no previous analyses of the global burden of childhood cancer represented in disability-adjusted life-years (DALYs). Methods: Using the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017 methodology, childhood (ages 0–19 years) cancer mortality was estimated by use of vital registration system data, verbal autopsy data, and population-based cancer registry incidence...
Apnea bradycardia detection based on new coupled hidden semi Markov model
, Article Medical and Biological Engineering and Computing ; 12 November , 2020 ; Shamsollahi, M. B ; Ge, D ; Beuchee, A ; Hernandez, A. I ; Sharif University of Technology
Springer Science and Business Media Deutschland GmbH
2020
Abstract
In this paper, a method for apnea bradycardia detection in preterm infants is presented based on coupled hidden semi Markov model (CHSMM). CHSMM is a generalization of hidden Markov models (HMM) used for modeling mutual interactions among different observations of a stochastic process through using finite number of hidden states with corresponding resting time. We introduce a new set of equations for CHSMM to be integrated in a detection algorithm. The detection algorithm was evaluated on a simulated data to detect a specific dynamic and on a clinical dataset of electrocardiogram signals collected from preterm infants for early detection of apnea bradycardia episodes. For simulated data, the...
Prevalence of influenza a infection in the middle-east: a systematic review and meta-analysis
, Article Clinical Respiratory Journal ; Volume 12, Issue 5 , 2018 , Pages 1787-1801 ; 17526981 (ISSN) ; Monavari, H. R ; Mostafaei, S ; Hadifar, S ; Ghasemi, A ; Babaei, F ; Kavosi, H ; Tavakoli, A ; Javanmard, D ; Esghaei, M ; Khodabandehlou, N ; Sharif University of Technology
Blackwell Publishing Ltd
2018
Abstract
Objective: This systematic review and meta-analysis was performed to determine the prevalence rate of influenza virus from different parts of Middle East region, and present an overall relative frequency (RF) for this region. Methods: The authors performed a systematic literature review from several reliable databases such as PubMed, ISI Web of Science and Scopus during 2000–2016. Furthermore, the keywords of this research were ‘Influenza’, ‘Subtype’, ‘Seroprevalence’, ‘Incidence’, ‘Seroepidemiology’, ‘H1N1’, ‘H3N2’, ‘H5N1’, ‘H9N2’, ‘Middle-East’ and ‘Meta-analysis’. The reported data were selected according to inclusion and exclusion criteria. Results: The authors selected 71 studies out of...
Public ingestion exposure to 226Ra in Ramsar, Iran
, Article Journal of Environmental Radioactivity ; Volume 198 , 2019 , Pages 11-17 ; 0265931X (ISSN) ; Salehi, A. A ; Naddafi, K ; Kardan, M. R ; Yunesian, M ; Nodehi, R. N ; Deevband, M. R ; Shooshtari, M. G ; Sharif University of Technology
Elsevier Ltd
2019
Abstract
Ramsar, in the north of Iran by the Caspian Sea, has been known for the highest natural radiation background on Earth due to the local geology and hydrogeology. The residents and visitors use the hot springs that distribute the natural radionuclides especially 226Ra and its decay products in the areas. Many studies have been undertaken to measure the absorbed dose rate in Ramsar's air, however, no survey has been done to assess public internal exposure from ingestion of natural radionuclides, such as, a broad survey for 226Ra was conducted in foodstuffs and drinking water. This study presents the results of public annual activity intake (Bq) and effective dose (μSv) from ingestion of 226Ra...
Size-dependent genotoxicity of graphene nanoplatelets in human stem cells
, Article Biomaterials ; Volume 33, Issue 32 , 2012 , Pages 8017-8025 ; 01429612 (ISSN) ; Ghaderi, E ; Akhavan, A ; Sharif University of Technology
2012
Abstract
Reduced graphene oxide nanoplatelets (rGONPs) were synthesized by sonication of covalently PEGylated GO sheets followed by a chemical reduction using hydrazine and bovine serum albumin. Human mesenchymal stem cells (hMSCs), as a fundamental factor in tissue engineering, were isolated from umbilical cord blood (as a recently proposed source for extracting fresh hMSCs) to investigate, for the first time, the size-dependent cyto- and geno-toxic effects of the rGONPs on the cells. The cell viability test showed significant cell destructions by 1.0 μg/mL rGONPs with average lateral dimensions (ALDs) of 11±4 nm, while the rGO sheets with ALDs of 3.8±0.4 μm could exhibit a significant cytotoxic...