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    Mathematical modeling of dermal wound healing: A numerical solution

    , Article 2010 The 2nd International Conference on Computer and Automation Engineering, ICCAE 2010, 26 February 2010 through 28 February 2010, Singapore ; Volume 2 , 2010 , Pages 153-156 ; 9781424455850 (ISBN) Azizi, A ; Ghaemi Osgouie, K ; Sharif University of Technology
    2010
    Abstract
    Though wound healing process is well-researched, this area is poorly known. One reason is that all interactions have not been discovered, the main reason, though, is that the involved processes interact in a very complicated manner with nonlinear feedback. Such complex feedback mechanisms can be easily addressed by mathematical modeling. This paper contains a review of the mathematical modeling of cell interaction with extracellular matrix components during the process of dermal wound healing with focusing on remodeling phase. The models are of partial differential equation type and solved by numerical method  

    Dermal wound healing-remodeling phase: A biological review

    , Article 2010 The 2nd International Conference on Computer and Automation Engineering, ICCAE 2010, 26 February 2010 through 28 February 2010, Singapore ; Volume 2 , 2010 , Pages 88-90 ; 9781424455850 (ISBN) Azizi, A ; Ghaemi Osgouie, K ; Sharif University of Technology
    2010
    Abstract
    Though wound healing process is well-researched, this area is poorly known. One reason is that all interactions have not been discovered, the main reason, though, is that the involved processes interact in a very complicated manner with nonlinear feedback. Such complex feedback mechanisms can be easily addressed by mathematical modeling. This paper contains a review of the mathematical modeling of cell interaction with extracellular matrix components during the process of dermal wound healing with focusing on remodeling phase. The models are of partial differential equation type and solved by finite element method  

    Single peak analysis of proton induced prompt gamma counts

    , Article Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms ; Volume 475 , 2020 , Pages 63-70 Saheli, F ; Vosoughi, N ; Riazi, Z ; Shahabinejad, H ; Rasouli, F. S ; Sharif University of Technology
    Elsevier B.V  2020
    Abstract
    Online elemental analysis of irradiated tissues is an important challenge in proton therapy for estimating the depth of the Bragg peak and monitoring the healing process. In the present study, the prompt gamma (PG) spectra of the most abundant elements of human tissues were obtained for two different incident protons of 30 MeV and 120 MeV using the Geant4 toolkit. Train phantoms were defined to study the elemental analysis of the tissue from PG spectra. It was found that the intensities of 7.12 and 3.91 MeV PG depend on the mass of 16O and 20Ca elements for both proton energies, respectively. Furthermore, multi-variable linear functions were presented for overlapping peaks like 4.44 and 2.31... 

    Longitudinal quantitative assessment of covid-19 infection progression from chest CTs

    , Article 24th International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2021, 27 September 2021 through 1 October 2021 ; Volume 12907 LNCS , 2021 , Pages 273-282 ; 03029743 (ISSN); 9783030872335 (ISBN) Kim, S. T ; Goli, L ; Paschali, M ; Khakzar, A ; Keicher, M ; Czempiel, T ; Burian, E ; Braren, R ; Navab, N ; Wendler, T ; Sharif University of Technology
    Springer Science and Business Media Deutschland GmbH  2021
    Abstract
    Chest computed tomography (CT) has played an essential diagnostic role in assessing patients with COVID-19 by showing disease-specific image features such as ground-glass opacity and consolidation. Image segmentation methods have proven to help quantify the disease and even help predict the outcome. The availability of longitudinal CT series may also result in an efficient and effective method to reliably assess the progression of COVID-19, monitor the healing process and the response to different therapeutic strategies. In this paper, we propose a new framework to identify infection at a voxel level (identification of healthy lung, consolidation, and ground-glass opacity) and visualize the... 

    Modeling of forced dermal wound healing using intelligent techniques

    , Article 2010 The 2nd International Conference on Computer and Automation Engineering, ICCAE 2010, 26 February 2010 through 28 February 2010, Singapore ; Volume 2 , 2010 , Pages 207-211 ; 9781424455850 (ISBN) Azizi, A ; Ghaemi Osgouie, K ; Sharif University of Technology
    2010
    Abstract
    Wound healing is a complex biological process dependent on multiple variables: tissue oxygenation, wound size, contamination, etc. Many of these factors depend on multiple factors themselves. Mechanisms for some interactions between these factors are still unknown but it is generally accepted that collagen synthesis, accumulation and organization are increased by mechanical stimuli, resulting in a forced healing process which improves mechanical properties of the damaged tissue. In this paper we focus on the neural networks and regard them as function approximators, and attempt to simulate remodeling phase of dermal wound healing process using neural networks as an intelligent technique  

    Mathematical modeling of dermal wound healing's remodeling phase: a finite element solution

    , Article 2009 International Association of Computer Science and Information Technology - Spring Conference, IACSIT-SC 2009, Singapore, 17 April 2009 through 20 April 2009 ; 2009 , Pages 529-532 ; 9780769536538 (ISBN) Azizi, A ; Seifipour, N ; Sharif University of Technology
    2009
    Abstract
    Though wound healing process is well-researched, this area is poorly known. One reason is that all interactions have not been discovered, the main reason, though, is that the involved processes interact in a very complicated manner with nonlinear feedback. Such complex feedback mechanisms can be easily addressed by mathematical modeling. This paper contains a review of the mathematical modeling of cell interaction with extracellular matrix components during the process of dermal wound healing with focusing on remodeling phase. The models are of partial differential equation type and solved by finite element method. © 2009 IEEE  

    Freeze-gelled alginate/gelatin scaffolds for wound healing applications: An in vitro, in vivo study

    , Article Materials Science and Engineering C ; Volume 113 , 2020 Afjoul, H ; Shamloo, A ; Kamali, A ; Sharif University of Technology
    Elsevier Ltd  2020
    Abstract
    In this study, fabrication of a three-dimensional porous scaffold was performed using freeze gelation method. Recently, fabrication of scaffolds using polymer blends has become common for many tissue engineering applications due to their unique tunable properties. In this work, we fabricated alginate-gelatin porous hydrogels for wound healing application using a new method based on some modifications to the freeze-gelation method. Alginate and gelatin were mixed in three different ratios and the resulting solutions underwent freeze gelation to obtain 3D porous matrices. We analyzed the samples using different characterization tests. The scanning electron microscopy (SEM) results indicated...