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dielectrophoretic
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Dielectrophoretic cell sorting via sliding cells on 3D silicon microelectrodes
, Article Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS), 22 January 2017 through 26 January 2017 ; 2017 , Pages 147-150 ; 10846999 (ISSN) ; 9781509050789 (ISBN) ; Chan, M. L ; Roshan, K. A ; Yobas, L ; Sharif University of Technology
Abstract
This work presents an innovative design for a flow-through dielectrophoretic cell sorting based on silicon bulk microelectrodes featuring sidewall undercuts. The microelectrodes are configured into an interdigitated array with digits extending across the flow chamber at an oblique angle against the flow stream. Target cells under dielectrophoretic forces and hydrodynamic drag can slide along the digits to a dedicated outlet. The design has been showcased for continuous-flow sorting of viable and non-viable mammalian cells, achieving a throughput of 16,600 cells/min, an order of magnitude higher than those reported for existing continuous-flow cell sorting designs using thin-film or...
Proposing a high-efficiency dielectrophoretic system for separation of dead and live cells
, Article Scientia Iranica ; Volume 25, Issue 1 , 2018 , Pages 186-195 ; 10263098 (ISSN) ; Nassiri Nazif, K ; Soufi, A. M ; Saidi, M. S ; Sharif University of Technology
Sharif University of Technology
2018
Abstract
Recently, electrode-based Dielectrophoresis (eDEP) has been used for particle manipulation by means of triangular electrodes. In this theoretical and numerical study, a microchannel with quarter-of-ellipse electrodes is presented and a detailed comparison with triangular electrodes is provided. Electric field, resultant DEP force, and particle trajectories for each microchannel are evaluated by means of COMSOL Multiphysics 4.4. Afterwards, focusing and separation efficiencies of the systems are assessed and compared. Finally, separation efficiency of our proposed model for live and dead cells is compared with that of our previous model published in the literature [1]. It is demonstrated that...