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    Two statistical methods for resolving healthy individuals and those with congestive heart failure based on extended self-similarity and a recursive method

    , Article Journal of Biological Physics ; Volume 32, Issue 6 , 2006 , Pages 489-495 ; 00920606 (ISSN) Atyabi, F ; Livari, M. A ; Kaviani, K ; Rahimi Tabar , M. R ; Sharif University of Technology
    2006
    Abstract
    In this paper we introduce two methods for measuring irregularities in human heartbeat time series (HHTS). First we consider the multi-fractal structure of HHTS to distinguish healthy individuals and from those with congestive heart failure. In this way we modify the Extended Self-Similarity (ESS) method and apply it to HHTS. Our second approach is based on the recursive method, which we use to predict the duration of the next heartbeat by considering a few previous ones. We use standard physiological data and show that these approaches lead to very satisfactory methods to resolve the healthy and CHF individuals. These methods can be used potentially in portable electronic heart alarm... 

    Regeneration of stochastic processes: An inverse method

    , Article European Physical Journal B ; Volume 47, Issue 3 , 2005 , Pages 411-415 ; 14346028 (ISSN) Ghasemi, F ; Peinke, J ; Sahimi, M ; Rahimi Tabar, M. R ; Sharif University of Technology
    2005
    Abstract
    We propose a novel inverse method that utilizes a set of data to construct a simple equation that governs the stochastic process for which the data have been measured, hence enabling us to reconstruct the stochastic process. As an example, we analyze the stochasticity in the beat-to-beat fluctuations in the heart rates of healthy subjects as well as those with congestive heart failure. The inverse method provides a novel technique for distinguishing the two classes of subjects in terms of a drift and a diffusion coefficients which behave completely differently for the two classes of subjects, hence potentially providing a novel diagnostic tool for distinguishing healthy subjects from those... 

    Functional Modeling of Normal and CHF Heart and Control of Total Artificial Heart- An Optimizing Approach

    , Ph.D. Dissertation Sharif University of Technology Ravanshadi, Samin (Author) ; Jahed, Mehran (Supervisor)
    Abstract
    World-wide, Congestive Heart Failure (CHF) takes hundreds of thousands of lives each year. This chronic heart disease causes poor performance of the heart and insufficient blood pumping to the organs. A significant percentage of patients with CHF require heart transplants for their survival. The high cost of heart transplant, shortage of donor hearts and possibility of its rejection by recipients are serious problems of this type of treatment. Therefore a large number of heart patients are potential beneficiaries of artificial blood pumps such as Ventricular Assist Device (VAD) and Total Artificial Heart (TAH). Performance of these systems must be compliant and complementary to the existing... 

    Modeling and Intelligent Control of Heart Assist Device

    , M.Sc. Thesis Sharif University of Technology Takhtechian, Parisa (Author) ; Jahed, Mehran (Supervisor)
    Abstract
    Congestive heart Failure (CHF) which occurs when the heart is no longer able to pump the blood sufficiently is a worldwide growing health concern. In the U.S. alone, an estimated 8 million people will be diagnosed with heart failure by 2030.Cardiac transplantation with limitations in donor availability, cannot solely resolve this global health concern. Therefore many patients must use alternative remedies, namely Artificial Heart and Ventricle Assist Device (VAD). The Left Ventricular Assist Device (LVAD) is a mechanical pump that is implanted in patients with congestive heart failure to help the left ventricle in pumping blood to the circulatory system. They are known to... 

    Design and Implementation of Bio-impedance Sensor Circuits

    , M.Sc. Thesis Sharif University of Technology Siamian Gorji, Reza (Author) ; Sharifkhani, Mohammad (Supervisor)
    Abstract
    Heart failure is a chronic and significant disease that affects millions of people worldwide. Despite advances in medical technology and treatment options, heart failure remains a leading cause of death globally. This has led to a growing interest in developing new diagnostic tools and therapeutic strategies that can improve the control of this disease. One promising field is bioimpedance spectroscopy, which is a non-invasive method for measuring the electrical properties of biological tissues in the body. Monitoring the condition of fluid accumulation in the lungs of heart failure patients is effective in reducing the death rate caused by this disease. In this thesis, a portable device for... 

    Analysis of non-stationary data for heart-rate fluctuations in terms of drift and diffusion coefficients

    , Article Journal of Biological Physics ; Volume 32, Issue 2 , 2006 , Pages 117-128 ; 00920606 (ISSN) Ghasemi, F ; Sahimi, M ; Peinke, J ; Rahimi Tabar, M. R ; Sharif University of Technology
    2006
    Abstract
    We describe a method for analyzing the stochasticity in non-stationary data for the beat-to-beat fluctuations in the heart rates of healthy subjects, as well as those with congestive heart failure. The method analyzes the return time series of the data as a Markov process, and computes the Markov time scale, i.e., the time scale over which the data are a Markov process. We also construct an effective stochastic continuum equation for the return series. We show that the drift and diffusion coefficients, as well as the amplitude of the return time series for healthy subjects are distinct from those with CHF. Thus, the method may potentially provide a diagnostic tool for distinguishing healthy... 

    A novel distributed model of the heart under normal and congestive heart failure conditions

    , Article Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine ; Volume 227, Issue 4 , 2013 , Pages 362-372 ; 09544119 (ISSN) Ravanshadi, S ; Jahed, M ; Sharif University of Technology
    2013
    Abstract
    Conventional models of cardiovascular system frequently lack required detail and focus primarily on the overall relationship between pressure, flow and volume. This study proposes a localized and regional model of the cardiovascular system. It utilizes noninvasive blood flow and pressure seed data and temporal cardiac muscle regional activity to predict the operation of the heart under normal and congestive heart failure conditions. The analysis considers specific regions of the heart, namely, base, mid and apex of left ventricle. The proposed method of parameter estimation for hydraulic electric analogy model is recursive least squares algorithm. Based on simulation results and comparison... 

    Design and Simulation of Bioimpedance Chip for Monitoring Heart Failure

    , M.Sc. Thesis Sharif University of Technology Rezapour, Mojtaba (Author) ; Sharifkhani, Mohammad (Supervisor)
    Abstract
    Cardiovascular disease is one of the leading causes of death and mortality. among these diseases, heart muscle inability, especially acute decompensated heart failure is very common. There are several methods to diagnose and monitor this disease, but a method that is accurate, non-invasive, portable and easy to access and easy to measure without multiple visits to the clinic; Priority for use. Early detection and continuous monitoring of fluid status by measuring the bio-impedance (Bio-Z) measurement of thoracic magnitude or phase is critical in reducing the mortality of chronic heart failure (CHF) patients. In this dissertation, for monitoring chronic heart failure, bio-impedance chips with...