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    AntAngioCOOL: computational detection of anti-angiogenic peptides

    , Article Journal of Translational Medicine ; Volume 17, Issue 1 , 2019 ; 14795876 (ISSN) Zahiri, J ; Khorsand, B ; Yousefi, A. A ; Kargar, M. J ; Shirali Hossein Zade, R ; Mahdevar, G ; Sharif University of Technology
    BioMed Central Ltd  2019
    Abstract
    Background: Angiogenesis inhibition research is a cutting edge area in angiogenesis-dependent disease therapy, especially in cancer therapy. Recently, studies on anti-angiogenic peptides have provided promising results in the field of cancer treatment. Methods: A non-redundant dataset of 135 anti-angiogenic peptides (positive instances) and 135 non anti-angiogenic peptides (negative instances) was used in this study. Also, 20% of each class were selected to construct an independent test dataset (see Additional files 1, 2). We proposed an effective machine learning based R package (AntAngioCOOL) to predict anti-angiogenic peptides. We have examined more than 200 different classifiers to build... 

    Effects of bacillus amyloliquefaciens lfb112 on growth performance, carcass traits, immune, and serum biochemical response in broiler chickens

    , Article Antibiotics ; Volume 10, Issue 11 , 2021 ; 20796382 (ISSN) Ahmat, M ; Cheng, J ; Abbas, Z ; Cheng, Q ; Fan, Z ; Ahmad, B ; Hou, M ; Osman, G ; Guo, H ; Wang, J ; Zhang, R ; Sharif University of Technology
    MDPI  2021
    Abstract
    This study aimed to investigate the effects of Bacillus amyloliquefaciens LFB112 on the growth performance, carcass traits, immune response, and serum biochemical parameters of broiler chickens. A total of 396 1 day old, mixed-sex commercial Ross 308 broilers with similar body weights were allotted into six treatment groups. The assigned groups were the CON group (basal diet with no supplement), AB (antibiotics) group (basal diet + 150 mg of aureomycin/kg), C+M group (basal diet + 5 × 108 CFU/kg B. amyloliquefaciens LFB112 powder with vegetative cells + metabolites), C group (basal diet + 5 × 108 CFU/kg B. amyloliquefaciens LFB112 vegetative cell powder with removed metabolites), M group... 

    Effects of bacillus amyloliquefaciens lfb112 on growth performance, carcass traits, immune, and serum biochemical response in broiler chickens

    , Article Antibiotics ; Volume 10, Issue 11 , 2021 ; 20796382 (ISSN) Ahmat, M ; Cheng, J ; Abbas, Z ; Cheng, Q ; Fan, Z ; Ahmad, B ; Hou, M ; Osman, G ; Guo, H ; Wang, J ; Zhang, R ; Sharif University of Technology
    MDPI  2021
    Abstract
    This study aimed to investigate the effects of Bacillus amyloliquefaciens LFB112 on the growth performance, carcass traits, immune response, and serum biochemical parameters of broiler chickens. A total of 396 1 day old, mixed-sex commercial Ross 308 broilers with similar body weights were allotted into six treatment groups. The assigned groups were the CON group (basal diet with no supplement), AB (antibiotics) group (basal diet + 150 mg of aureomycin/kg), C+M group (basal diet + 5 × 108 CFU/kg B. amyloliquefaciens LFB112 powder with vegetative cells + metabolites), C group (basal diet + 5 × 108 CFU/kg B. amyloliquefaciens LFB112 vegetative cell powder with removed metabolites), M group...