Sharif Digital Repository

In the present study, the influence of the liver vascular bed on heat transfer in a tumor located close to the hepatic artery and exposed to high intensity focused ultrasound (HIFU), is studied numerically. For this purpose, an acoustics-thermal-fluid coupling model based on the porous media theory under the local thermal non-equilibrium assumption is used to calculate the temperature field in the tumor, porous liver, and the hepatic artery. Different generations of the liver vasculature including arterial branches, terminal arterial branches, terminal veins and venous branches are examined at different porosities (the volume fraction of the vasculature). It is found that the liver... 

In this study, the influence of vascular bed comprising terminal arterial branches on heat transfer in a liver tumor exposed to high intensity focused ultrasound (HIFU) is studied numerically. Also, the effect of vascular density on temperature distribution is investigated. A coupled set of acoustics, thermal, and fluid models is used to calculate the temperature distribution in the liver. The numerical model is established based on the Westervelt and bioheat equations along with the Navier-Stokes equations. Moreover, the acoustic streaming effect is included with Newtonian and non-Newtonian flow assumptions. It is found that in a vascular bed comprising terminal arterial branches, the...