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Viral and non-viral gene therapy using 3D (bio)printing
, Article Journal of Gene Medicine ; Volume 24, Issue 12 , 2022 ; 1099498X (ISSN) ; Rahimnejad, M ; Nasrollahi Boroujeni, N ; Ahmadi, Z ; Motamed Fath, P ; Ahmadi, S ; Safarkhani, M ; Rabiee, N ; Sharif University of Technology
John Wiley and Sons Inc
2022
Abstract
The overall success in launching discovered drugs is tightly restricted to the high rate of late-stage failures, which ultimately inhibits the distribution of medicines in markets. As a result, it is imperative that methods reliably predict the effectiveness and, more critically, the toxicity of medicine early in the drug development process before clinical trials be continuously innovated. We must stay up to date with the fast appearance of new infections and diseases by rapidly developing the requisite vaccinations and medicines. Modern in vitro models of disease may be used as an alternative to traditional disease models, and advanced technology can be used for the creation of...