Sharif Digital Repository

Since we are exposed to many air pollutants such as different gases daily, this project has attempted to investigate how these gases affect nucleobases, which are the main constituent of the DNA chain. The gases used in this study are sulfur dioxide (SO2), carbon monoxide (CO) and nitric oxide (NO). Each of these gases was studied separately along with the most stable nucleobase in the neutral, anionic and cationic states. The AT and GC base pairs were also exposed to each of these gases and changes (for exampl, the acidity, proton affinity) created in the AT and GC base pairs were examined.The most important properties studied during this project include gas-nucleobase interactions, proton...